Y4QK_SINFN
ID Y4QK_SINFN Reviewed; 308 AA.
AC P55632;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 25-MAY-2022, entry version 120.
DE RecName: Full=Putative integrase/recombinase y4qK;
GN OrderedLocusNames=NGR_a01870; ORFNames=y4qK;
OS Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG Plasmid sym pNGR234a.
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=394;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 101917 / NGR234;
RX PubMed=9163424; DOI=10.1038/387394a0;
RA Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA Perret X.;
RT "Molecular basis of symbiosis between Rhizobium and legumes.";
RL Nature 387:394-401(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 101917 / NGR234;
RX PubMed=19376903; DOI=10.1128/aem.00515-09;
RA Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT systems.";
RL Appl. Environ. Microbiol. 75:4035-4045(2009).
CC -!- FUNCTION: May function as an integrase.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
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DR EMBL; U00090; AAB92466.1; -; Genomic_DNA.
DR RefSeq; NP_444038.1; NC_000914.2.
DR AlphaFoldDB; P55632; -.
DR SMR; P55632; -.
DR STRING; 394.NGR_a01870; -.
DR EnsemblBacteria; AAB92466; AAB92466; NGR_a01870.
DR KEGG; rhi:NGR_a01870; -.
DR PATRIC; fig|394.7.peg.186; -.
DR eggNOG; COG4974; Bacteria.
DR HOGENOM; CLU_027562_9_5_5; -.
DR OMA; TLERDWV; -.
DR OrthoDB; 745068at2; -.
DR Proteomes; UP000001054; Plasmid sym pNGR234a.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 1.10.443.10; -; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR Pfam; PF13495; Phage_int_SAM_4; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; SSF56349; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration; DNA recombination; DNA-binding; Plasmid;
KW Reference proteome; Transposable element; Viral genome integration;
KW Virus entry into host cell.
FT CHAIN 1..308
FT /note="Putative integrase/recombinase y4qK"
FT /id="PRO_0000197574"
FT DOMAIN 15..97
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01248"
FT DOMAIN 115..288
FT /note="Tyr recombinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 150
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 175
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 240
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 243
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 266
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 275
FT /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ SEQUENCE 308 AA; 34958 MW; EC988118DEF98C15 CRC64;
MGRLFGSLFH QTEELVMTPL RQRMSEDMQV RNFSLNTQLS YLRQVSLFAR HFGKAPDLLG
REDIRTYQVY LANEKKLAPN SIHIAIAALR FFFSVTLERD WVPAEVLPLP KKPQKLPIIL
SPDEVQHFLG CVLDLKHHAI LTTCYAAGLR ISEAVQLKPT DIDSQRMVVR VEQGKGQKDR
YVMLSPKLLE ILRDYWRMPR PKEWLFPGDR AGHPITRDAV GQACAKAHDL SRLSKPVTPH
SLRHAFAVHL LEAGADVRTI QLLLGHRSLA TTAHYLRIAT NKVCATSSPF ELLPRPAPTP
PPAKPEYF