ID   Y4RE_SINFN              Reviewed;         310 AA.
AC   P55638;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Putative integrase/recombinase y4rE;
GN   OrderedLocusNames=NGR_a01820; ORFNames=y4rE;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
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DR   EMBL; U00090; AAB92471.1; -; Genomic_DNA.
DR   RefSeq; NP_444043.1; NC_000914.2.
DR   RefSeq; WP_010875216.1; NC_000914.2.
DR   AlphaFoldDB; P55638; -.
DR   SMR; P55638; -.
DR   STRING; 394.NGR_a01820; -.
DR   EnsemblBacteria; AAB92471; AAB92471; NGR_a01820.
DR   KEGG; rhi:NGR_a01820; -.
DR   PATRIC; fig|394.7.peg.180; -.
DR   eggNOG; COG0582; Bacteria.
DR   HOGENOM; CLU_027562_10_0_5; -.
DR   OMA; WHQQRAN; -.
DR   OrthoDB; 745068at2; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.443.10; -; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA integration; DNA recombination; DNA-binding; Plasmid;
KW   Reference proteome; Transposable element; Viral genome integration;
KW   Virus entry into host cell.
FT   CHAIN           1..310
FT                   /note="Putative integrase/recombinase y4rE"
FT                   /id="PRO_0000197581"
FT   DOMAIN          6..83
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01248"
FT   DOMAIN          104..301
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        148
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        173
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        245
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        248
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        279
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        288
FT                   /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ   SEQUENCE   310 AA;  34358 MW;  90D7EF366CDB5C7A CRC64;
     MTAFARFLGE KVERYIDLRH SLGYAFSKQA GTLRAFVRYV ERAQFDAPAT RTMALDFVLS
     FGGAANSRAT RHGVLRRFYE YLAVYDAQTE ALKRRAFPRS RAIPPPRILS EAELASLIDA
     CARISPGIPL RGLTMATLIG LLASSGLRSG EVVRLDRSDV DLTNGVLLVR KTKFRKDRLV
     PVHATTQTAL CRYARERDAA FPSPKDQAFF LSSRGNRLSA TGLQCGFAQV RKFAGLDDGK
     TLRPHDLRHR FAVTRMSLWH QQRANVQALL PVLATYLGHA NYSDTAYYLT GSVDLLAMAA
     ERAFLDGGAA