ID   Y4RF_SINFN              Reviewed;         425 AA.
AC   P55639;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 121.
DE   RecName: Full=Putative integrase/recombinase y4rF;
GN   OrderedLocusNames=NGR_a01810; ORFNames=y4rF;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
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DR   EMBL; U00090; AAB92472.1; -; Genomic_DNA.
DR   RefSeq; NP_444044.1; NC_000914.2.
DR   AlphaFoldDB; P55639; -.
DR   SMR; P55639; -.
DR   STRING; 394.NGR_a01810; -.
DR   EnsemblBacteria; AAB92472; AAB92472; NGR_a01810.
DR   KEGG; rhi:NGR_a01810; -.
DR   PATRIC; fig|394.7.peg.179; -.
DR   eggNOG; COG0582; Bacteria.
DR   HOGENOM; CLU_027562_23_3_5; -.
DR   OMA; AGPLTHY; -.
DR   OrthoDB; 745068at2; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; -; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA integration; DNA recombination; DNA-binding; Plasmid;
KW   Reference proteome; Transposable element; Viral genome integration;
KW   Virus entry into host cell.
FT   CHAIN           1..425
FT                   /note="Putative integrase/recombinase y4rF"
FT                   /id="PRO_0000197582"
FT   DOMAIN          123..210
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01248"
FT   DOMAIN          233..418
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        273
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        298
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        370
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        373
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        396
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        405
FT                   /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ   SEQUENCE   425 AA;  47384 MW;  39B3CD8BBEA27EF5 CRC64;
     MRDPPAPLFR RDNMLEFYFS YRGVLKRLRS GALGGEMDRL AEHFLTLGYK RASAKIYLSR
     VARFSQFAAT RCGLMPIHQD VIDSYLGTFT TDTPRIGAVS ALAHARRVAP ERFIIPVPSE
     EADPDALLLA SFSDYLRTVR GLEPKTREGI LLGGRRFLDW FRHRHPGQNL EALTAEHVLA
     AVEHRLSLSA TSGTRTAATS HIRTFLRFLC WAGHHRQDLA RIVPRTPYWR LAHLPPRLAW
     GDVRRAIDAI GATTPVAIRD RAVLLLLATT GIRNGELRAI RLQDIDWRTG EVFIRRTKGK
     RDRVVPLLEE TGAALVDYIL RARPKVDSPY LFLSFTPPVG AFKSAAPVSR IVRKRLRHGG
     VELGRVAGAH LLRHSLATQL VGQRRPINEV ADLLGHRSIN TTALYVKVAA SQLAEVALPF
     PGGAA