ID   Y4SI_SINFN              Reviewed;         756 AA.
AC   P55652;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 135.
DE   RecName: Full=Probable chemoreceptor y4sI;
DE   AltName: Full=Methyl-accepting chemotaxis protein;
GN   OrderedLocusNames=NGR_a01640; ORFNames=y4sI;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: Chemotactic-signal transducers respond to changes in the
CC       concentration of attractants and repellents in the environment,
CC       transduce a signal from the outside to the inside of the cell, and
CC       facilitate sensory adaptation through the variation of the level of
CC       methylation. Attractants increase the level of methylation while
CC       repellents decrease the level of methylation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000305}.
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DR   EMBL; U00090; AAB91848.1; -; Genomic_DNA.
DR   PIR; S43964; S43964.
DR   RefSeq; NP_444061.1; NC_000914.2.
DR   RefSeq; WP_010875200.1; NC_000914.2.
DR   AlphaFoldDB; P55652; -.
DR   SMR; P55652; -.
DR   STRING; 394.NGR_a01640; -.
DR   PRIDE; P55652; -.
DR   EnsemblBacteria; AAB91848; AAB91848; NGR_a01640.
DR   KEGG; rhi:NGR_a01640; -.
DR   PATRIC; fig|394.7.peg.154; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_12_5; -.
DR   OrthoDB; 429006at2; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 2.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Chemotaxis; Membrane; Methylation; Plasmid;
KW   Reference proteome; Repeat; Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..756
FT                   /note="Probable chemoreceptor y4sI"
FT                   /id="PRO_0000110570"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        330..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          353..406
FT                   /note="HAMP 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00102"
FT   DOMAIN          434..486
FT                   /note="HAMP 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00102"
FT   DOMAIN          491..720
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00284"
FT   REGION          736..756
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   756 AA;  79979 MW;  07D788972DBFA5F4 CRC64;
     MGGRMPLLNV SPLKWPISLK IPAMTVCVAV LSCTTVATFA GITSVATTRS LIEKHLNYVA
     ISMRDALLTK LQATKFEVEG LSANPGLLQL FNNTSVGFAA VSPTDLTAAS VDKVESGKFS
     LAATPTTKFY VDNYQKLDAW LKPLAAKQSY SGILLANAEG AIIYSTGTNP VGPVDANGSI
     NLAIASSANS QEAVMTDFTP PTLSAPGQAL YAVAIVHPFI PDKRNGTLLI SMSTEMLNAV
     MGQAKGFGPH SEALIAGSDG KPRSLSSISR DEDAEAVVNS DLLSQGIKTS NFGAQEVLSA
     SQQLKWQDHQ WSIIALEPEA DVVSASTAML IKIIGITAAT AILALAMAIL ASRSISGPLA
     GLVSIMKRLA NGDINVRVAG VDRRDEMGEM SRAVLVFRDN AIARVAAEDD ARSAEEAMEH
     DRRMMEMERS ERLDEQARVM AQIGGGLAAL SDGVFSRPIT VDFPEEYRPL KSDFNRALGQ
     LRETIRTVAA QAASMSSIVS EISCATDVLA KRTEHQAIVL DGAVNTMDAI SNDVSVTANA
     ANNADALVRD AHSAAAASDE IVSSAIAGML EIEESSAKIA TIVSVIEEIA HQTNLLALNA
     GVEASRAGEA GKGFAVVASE VRALAQRSSD AAKEIKDLIN VSTQRVERGK ELVDSASELL
     KHIAARVDLI RTTVSNIAAT ATSQAKHLSE FQTTIAEIDQ STQQTAAMAE ESDAACRSLN
     AEAQHLLELI QQFELGGGSS TRQPQSPPTQ RYFMSR