Y500A_MYCTU
ID Y500A_MYCTU Reviewed; 78 AA.
AC P9WKT7; L0T3Y2; Q6MX35; Q8VKK5;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Putative DNA-binding protein Rv0500A;
GN OrderedLocusNames=Rv0500A;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION.
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=12368430; DOI=10.1099/00221287-148-10-2967;
RA Camus J.-C., Pryor M.J., Medigue C., Cole S.T.;
RT "Re-annotation of the genome sequence of Mycobacterium tuberculosis
RT H37Rv.";
RL Microbiology 148:2967-2973(2002).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR EMBL; AL123456; CCP43236.1; -; Genomic_DNA.
DR RefSeq; WP_003402437.1; NZ_NVQJ01000002.1.
DR RefSeq; YP_177624.1; NC_000962.3.
DR AlphaFoldDB; P9WKT7; -.
DR SMR; P9WKT7; -.
DR STRING; 83332.Rv0500A; -.
DR PaxDb; P9WKT7; -.
DR DNASU; 3205035; -.
DR GeneID; 3205035; -.
DR GeneID; 45424463; -.
DR KEGG; mtu:Rv0500A; -.
DR TubercuList; Rv0500A; -.
DR eggNOG; COG3311; Bacteria.
DR OMA; RYRWVMA; -.
DR PhylomeDB; P9WKT7; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR041657; HTH_17.
DR InterPro; IPR010093; SinI_DNA-bd.
DR Pfam; PF12728; HTH_17; 1.
DR SUPFAM; SSF46955; SSF46955; 1.
DR TIGRFAMs; TIGR01764; excise; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Reference proteome.
FT CHAIN 1..78
FT /note="Putative DNA-binding protein Rv0500A"
FT /id="PRO_0000399397"
FT DNA_BIND 24..45
FT /note="H-T-H motif"
FT /evidence="ECO:0000250"
SQ SEQUENCE 78 AA; 8508 MW; 42EE70900E906129 CRC64;
MTSTNGPSAR DTGFVEGQQA KTQLLTVAEV AALMRVSKMT VYRLVHNGEL PAVRVGRSFR
VHAKAVHDML ETSYFDAG