ID   Y500_BACTN              Reviewed;         532 AA.
AC   Q8AAG5;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Uncharacterized transporter BT_0500;
GN   OrderedLocusNames=BT_0500;
OS   Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS   CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=226186;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC   VPI-5482 / E50;
RX   PubMed=12663928; DOI=10.1126/science.1080029;
RA   Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA   Hooper L.V., Gordon J.I.;
RT   "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL   Science 299:2074-2076(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; AE015928; AAO75607.1; -; Genomic_DNA.
DR   RefSeq; NP_809413.1; NC_004663.1.
DR   RefSeq; WP_008765024.1; NC_004663.1.
DR   AlphaFoldDB; Q8AAG5; -.
DR   SMR; Q8AAG5; -.
DR   STRING; 226186.BT_0500; -.
DR   PaxDb; Q8AAG5; -.
DR   PRIDE; Q8AAG5; -.
DR   EnsemblBacteria; AAO75607; AAO75607; BT_0500.
DR   GeneID; 60926459; -.
DR   KEGG; bth:BT_0500; -.
DR   PATRIC; fig|226186.12.peg.501; -.
DR   eggNOG; COG0490; Bacteria.
DR   eggNOG; COG2985; Bacteria.
DR   HOGENOM; CLU_035023_3_0_10; -.
DR   InParanoid; Q8AAG5; -.
DR   OMA; RDGKNYF; -.
DR   Proteomes; UP000001414; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 2.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 2.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 2.
DR   PROSITE; PS51202; RCK_C; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..532
FT                   /note="Uncharacterized transporter BT_0500"
FT                   /id="PRO_0000208756"
FT   TRANSMEM        7..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        30..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        386..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        421..440
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        445..467
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        474..496
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        506..528
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          179..262
FT                   /note="RCK C-terminal 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
FT   DOMAIN          263..346
FT                   /note="RCK C-terminal 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ   SEQUENCE   532 AA;  56836 MW;  51223646CA5781DC CRC64;
     MFTDLLHSSY FSLFLIVALG FMLGRIKIKG LSLDVSAVIF IALLFGHFGV IIPKELGNFG
     LVLFIFTIGI QAGPGFFDSF RSKGKTLILI TMLIICSACL TAVGLKYAFD IDTPSVVGLI
     AGALTSTPGL AVAIDSTHSP LASIAYGIAY PFGVIGVILF VKLLPKIMRV NLDQEARRLE
     IERRGQFPEL GTCIYRVTNA SVFNRSLMQI NARAMTGAVI SRLKHKDEIS IPTAHTVLHE
     GDYIQAVGSE ESLNQLSVLI GEREEGELPL DKTQEIESLL LTKKDMINKQ LGDLNLQKNF
     GCTVTRVRRS GIDLSPSPDL ALKFGDKLMV VGEKEGIKGV ARLLGNNAKK LSDTDFFPIA
     MGIVLGVLFG KLNISFSDTL SFSPGLTGGV LMVALVLSAV GKTGPIIWSM SGPANQLLRQ
     LGLLLFLAEV GTSAGKNLVA TFQESGLLMF GVGAAITVVP MLVAVIVGRL VFKINILDLL
     GTITGGMTST PGLAAADSMV DSNIPSVAYA TVYPIAMVFL ILFIQVISSA VY