ID   Y500_PYRAB              Reviewed;         225 AA.
AC   Q9V1C7; G8ZGL0;
DT   18-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=UPF0173 metal-dependent hydrolase PYRAB05000 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=PYRAB05000; ORFNames=PAB0339;
OS   Pyrococcus abyssi (strain GE5 / Orsay).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=272844;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GE5 / Orsay;
RX   PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA   Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA   Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J.,
RA   Weissenbach J., Zivanovic Y., Forterre P.;
RT   "An integrated analysis of the genome of the hyperthermophilic archaeon
RT   Pyrococcus abyssi.";
RL   Mol. Microbiol. 47:1495-1512(2003).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=GE5 / Orsay;
RX   PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA   Gao J., Wang J.;
RT   "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT   Pyrococcus furiosus DSM 3638.";
RL   Curr. Microbiol. 64:118-129(2012).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ248284; CAB49422.1; -; Genomic_DNA.
DR   EMBL; HE613800; CCE69889.1; -; Genomic_DNA.
DR   PIR; G75167; G75167.
DR   RefSeq; WP_010867624.1; NC_000868.1.
DR   AlphaFoldDB; Q9V1C7; -.
DR   SMR; Q9V1C7; -.
DR   STRING; 272844.PAB0339; -.
DR   EnsemblBacteria; CAB49422; CAB49422; PAB0339.
DR   GeneID; 1495402; -.
DR   KEGG; pab:PAB0339; -.
DR   PATRIC; fig|272844.11.peg.535; -.
DR   eggNOG; arCOG00497; Archaea.
DR   HOGENOM; CLU_070010_4_0_2; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 76909at2157; -.
DR   PhylomeDB; Q9V1C7; -.
DR   Proteomes; UP000000810; Chromosome.
DR   Proteomes; UP000009139; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..225
FT                   /note="UPF0173 metal-dependent hydrolase PYRAB05000"
FT                   /id="PRO_0000156398"
SQ   SEQUENCE   225 AA;  24475 MW;  A41CC1041DB53CD6 CRC64;
     MVKVKFLGHA AFYIEGSKKI LIDPFLTGNP QAVAKPEDFK DVDLILVTHA HGDHIGDAGE
     IAKISGAKIV AMYDIANYIA EKFKGVETVG MNYGPTEVDG VFIVQVPAWH SSSDGKYSIG
     NASGFIVKLD GKTIYHAGDT YVFKDMELFS ELYGPIDVAL LPIGGHFTMG VKEAAKAVEL
     LKPRTVVPMH YNTWPPISAD PEEFKKLVGD KAKVVVLKPG EELEL