ID   Y5020_MYCMO             Reviewed;         363 AA.
AC   Q6KHE2;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Uncharacterized RNA methyltransferase MMOB5020;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MMOB5020;
OS   Mycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711) (Mesomycoplasma
OS   mobile).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mesomycoplasma.
OX   NCBI_TaxID=267748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43663 / 163K / NCTC 11711;
RX   PubMed=15289470; DOI=10.1101/gr.2674004;
RA   Jaffe J.D., Stange-Thomann N., Smith C., DeCaprio D., Fisher S., Butler J.,
RA   Calvo S., Elkins T., FitzGerald M.G., Hafez N., Kodira C.D., Major J.,
RA   Wang S., Wilkinson J., Nicol R., Nusbaum C., Birren B., Berg H.C.,
RA   Church G.M.;
RT   "The complete genome and proteome of Mycoplasma mobile.";
RL   Genome Res. 14:1447-1461(2004).
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RNA M5U methyltransferase family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01024}.
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DR   EMBL; AE017308; AAT27988.1; -; Genomic_DNA.
DR   RefSeq; WP_011265022.1; NC_006908.1.
DR   AlphaFoldDB; Q6KHE2; -.
DR   SMR; Q6KHE2; -.
DR   STRING; 267748.MMOB5020; -.
DR   EnsemblBacteria; AAT27988; AAT27988; MMOB5020.
DR   KEGG; mmo:MMOB5020; -.
DR   eggNOG; COG2265; Bacteria.
DR   HOGENOM; CLU_014689_1_0_14; -.
DR   OMA; GYELLHM; -.
DR   OrthoDB; 1421660at2; -.
DR   Proteomes; UP000009072; Chromosome.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 2.40.50.140; -; 1.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR030390; MeTrfase_TrmA_AS.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR010280; U5_MeTrfase_fam.
DR   PANTHER; PTHR11061; PTHR11061; 2.
DR   Pfam; PF05958; tRNA_U5-meth_tr; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS51687; SAM_MT_RNA_M5U; 1.
DR   PROSITE; PS01230; TRMA_1; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..363
FT                   /note="Uncharacterized RNA methyltransferase MMOB5020"
FT                   /id="PRO_0000162003"
FT   ACT_SITE        318
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01024"
FT   BINDING         198
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01024"
FT   BINDING         225
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01024"
FT   BINDING         246
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01024"
FT   BINDING         291
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01024"
SQ   SEQUENCE   363 AA;  42158 MW;  F78ACE2B47F61EFB CRC64;
     MIAELEIIFY SQKGEGVGFY LNKPTYVKGV IKGEKIKAFI YLESASFFKA RLVEILIESK
     NRNHDVPKLH YLIGGYELLH MNNTEQINFK KERVINDFKK IANYEISSLE LVQGKKLLHY
     RNKITLHYGS LYLANSNHKI KLAKSLLTDI NLKANKKEAE WIIRKLDTQI EGTKQTKIYT
     TDKMNGITFR VGLNSFYQVN KEVANLIYNQ ISEFINLNEN VLDLYSGIGT ISLLIAAKAK
     SVTGVERNLD SIEDANFNKE FNKIKNVNFI HQDVIKYLKQ NKTYFDTVIV DPARRGLEED
     IIELILKLKP QKIIYLSCNV GTQASNFNKF KHEYQIEFIK SYDMFPQTYH IESLMVLKKL
     NKQ