ID   Y5025_MYCGI             Reviewed;         307 AA.
AC   A4TEC9;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mflv_5025;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mflv_5025;
OS   Mycolicibacterium gilvum (strain PYR-GCK) (Mycobacterium gilvum (strain
OS   PYR-GCK)).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=350054;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PYR-GCK;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.;
RT   "Complete sequence of chromosome of Mycobacterium gilvum PYR-GCK.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000656; ABP47491.1; -; Genomic_DNA.
DR   RefSeq; WP_011895853.1; NC_009338.1.
DR   AlphaFoldDB; A4TEC9; -.
DR   SMR; A4TEC9; -.
DR   STRING; 350054.Mflv_5025; -.
DR   EnsemblBacteria; ABP47491; ABP47491; Mflv_5025.
DR   KEGG; mgi:Mflv_5025; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; FFIKMMD; -.
DR   OrthoDB; 847145at2; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..307
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mflv_5025"
FT                   /id="PRO_0000361157"
FT   BINDING         130
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         159..160
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   307 AA;  32687 MW;  330A3848EA756271 CRC64;
     MARTPDDSWD LASSVGATAT MVAAGRAVAS ADPDPLINDP YAEPLVRAVG LDFFTRMLDG
     ELDLSVFPDS SPERAQAMID GMAVRTRFFD DCCLAAASAG VRQVVILAAG LDARTYRLPW
     PDGTVVYELD QPDVIAFKTQ TLRNLGAEPA ATQRPVPVDL REDWPAALRA AGFDATRPTA
     WLAEGLLIYL PPEAQDALFD TVTALSAPGS TLATEYVPGI VDFDGAKARA LSEPLREHGL
     DIDMPSLVYT GARTPVMDHL RGAGWQVSGT ARAELFARFG RPLPQDADGT DPLGEIVYVS
     ATLAADA