ID   Y503_TREPA              Reviewed;         187 AA.
AC   O83516;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Uncharacterized lipoprotein TP_0503;
DE   Flags: Precursor;
GN   OrderedLocusNames=TP_0503;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000520; AAC65492.1; -; Genomic_DNA.
DR   PIR; C71317; C71317.
DR   RefSeq; WP_010881952.1; NC_021490.2.
DR   AlphaFoldDB; O83516; -.
DR   IntAct; O83516; 23.
DR   STRING; 243276.TPANIC_0503; -.
DR   EnsemblBacteria; AAC65492; AAC65492; TP_0503.
DR   GeneID; 57879024; -.
DR   KEGG; tpa:TP_0503; -.
DR   eggNOG; ENOG503450S; Bacteria.
DR   HOGENOM; CLU_118622_1_0_12; -.
DR   OMA; MVINETP; -.
DR   OrthoDB; 1542115at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           18..187
FT                   /note="Uncharacterized lipoprotein TP_0503"
FT                   /id="PRO_0000014252"
FT   LIPID           18
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           18
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   187 AA;  21410 MW;  C96F2AE1D1C80A64 CRC64;
     MYAGGRVVRS AFARGKVCYL IGSVLWGSVS CTQPRVQKWV QNDGKVNVHS PQERAGVVAT
     FGTVRITRSD YERTKAELQD VVAHLNRITA ERDYHKWLVY LSDAYRRAYS MPDILQQSSD
     ALPKKGVRLR HLRDYFIHVF VPSRQNVRVD SIVFESPTRV DVIMNHGGKA LLVYKIEKIH
     SAWKLLP