ID   Y5049_STRCO             Reviewed;         196 AA.
AC   Q9FBN0;
DT   02-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Putative NADH dehydrogenase/NAD(P)H nitroreductase SCO5049 {ECO:0000255|HAMAP-Rule:MF_01204};
DE            EC=1.-.-.- {ECO:0000255|HAMAP-Rule:MF_01204};
GN   OrderedLocusNames=SCO5049; ORFNames=SCK7.22c;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01204};
CC   -!- SIMILARITY: Belongs to the nitroreductase family. HadB/RutE subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01204}.
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DR   EMBL; AL939122; CAC05894.1; -; Genomic_DNA.
DR   RefSeq; NP_629201.1; NC_003888.3.
DR   RefSeq; WP_003973928.1; NZ_VNID01000008.1.
DR   AlphaFoldDB; Q9FBN0; -.
DR   SMR; Q9FBN0; -.
DR   STRING; 100226.SCO5049; -.
DR   GeneID; 1100490; -.
DR   KEGG; sco:SCO5049; -.
DR   PATRIC; fig|100226.15.peg.5129; -.
DR   eggNOG; COG0778; Bacteria.
DR   HOGENOM; CLU_084441_0_0_11; -.
DR   InParanoid; Q9FBN0; -.
DR   OMA; LMVVNIG; -.
DR   PhylomeDB; Q9FBN0; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-UniRule.
DR   CDD; cd02148; RutE-like; 1.
DR   Gene3D; 3.40.109.10; -; 1.
DR   HAMAP; MF_01204; Oxidoreductase_RutE_HadB; 1.
DR   InterPro; IPR029479; Nitroreductase.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   InterPro; IPR023936; RutE-like.
DR   Pfam; PF00881; Nitroreductase; 1.
DR   SUPFAM; SSF55469; SSF55469; 1.
PE   3: Inferred from homology;
KW   Flavoprotein; FMN; NAD; NADP; Oxidoreductase; Reference proteome.
FT   CHAIN           1..196
FT                   /note="Putative NADH dehydrogenase/NAD(P)H nitroreductase
FT                   SCO5049"
FT                   /id="PRO_0000072732"
SQ   SEQUENCE   196 AA;  21473 MW;  F29AF0C8830F954B CRC64;
     MSLVLDPAAQ DLLFREARTA NTFTDEPVTD EQVQAIYDLV KYGPTAFNQS PLRITLVRSP
     EARERLVAHM AEGNRPKTAA APLVAILSAD NEFHEELPEL FPHFPAAKDA FFSERPVREG
     AATLNAALQA AYFIVGVRAA GLAAGPMTGL DFEGVRKEFL DDDHTPLMVV NIGRPGPDAW
     FPRSPRLAYD QVVTTV