ID   Y505_RICPR              Reviewed;         319 AA.
AC   Q9ZD42;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Uncharacterized protein RP505;
GN   OrderedLocusNames=RP505;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- SIMILARITY: Belongs to the SIS family. GutQ/KpsF subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ235272; CAA14957.1; -; Genomic_DNA.
DR   PIR; C71654; C71654.
DR   RefSeq; NP_220881.1; NC_000963.1.
DR   RefSeq; WP_004597752.1; NC_000963.1.
DR   AlphaFoldDB; Q9ZD42; -.
DR   SMR; Q9ZD42; -.
DR   STRING; 272947.RP505; -.
DR   EnsemblBacteria; CAA14957; CAA14957; CAA14957.
DR   GeneID; 57569627; -.
DR   KEGG; rpr:RP505; -.
DR   PATRIC; fig|272947.5.peg.514; -.
DR   eggNOG; COG0517; Bacteria.
DR   eggNOG; COG0794; Bacteria.
DR   HOGENOM; CLU_040681_13_1_5; -.
DR   OMA; LMACLMR; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016853; F:isomerase activity; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd05014; SIS_Kpsf; 1.
DR   Gene3D; 3.10.580.10; -; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR004800; KdsD/KpsF-type.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   InterPro; IPR035474; SIS_Kpsf.
DR   Pfam; PF00571; CBS; 2.
DR   Pfam; PF01380; SIS; 1.
DR   PIRSF; PIRSF004692; KdsD_KpsF; 1.
DR   SMART; SM00116; CBS; 2.
DR   SUPFAM; SSF53697; SSF53697; 1.
DR   TIGRFAMs; TIGR00393; kpsF; 1.
DR   PROSITE; PS51371; CBS; 2.
DR   PROSITE; PS51464; SIS; 1.
PE   3: Inferred from homology;
KW   ATP-binding; CBS domain; Nucleotide-binding; Reference proteome; Repeat.
FT   CHAIN           1..319
FT                   /note="Uncharacterized protein RP505"
FT                   /id="PRO_0000136589"
FT   DOMAIN          36..178
FT                   /note="SIS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00797"
FT   DOMAIN          203..263
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          268..319
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   BINDING         51..56
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   319 AA;  35297 MW;  57211D5A222F48D8 CRC64;
     MINTNNYRII AKRVISSATS ALETLSNNIP SDFNRIIEFL LSFKGRIILT GIGKSGYIAR
     KIAASFSSTG MPSFYLHPAE ASHGDLGMIT RNDLVMMLSN SGETKELFNI IEYCNNSSIK
     IAAMTMNKNS TLAKRSDFLL KIPECQEASL IGTPTISSLI MLSLGDAIMT VIHEERGFTR
     DDFKIYHPGG TIGANLTKIK NIMRSGDEIP LVYEDTSFTE TIIIMNKKRL GCTLVTDKEQ
     NLIGIITDGD LRRNIHDQIH LKTASSIMTK NPHYISSEIF AQEALNLMKA KNITNIPIVD
     DNIIIGIIHI HDLLSMGVS