Y5064_ARATH
ID Y5064_ARATH Reviewed; 548 AA.
AC P0DH79; Q9LUF7;
DT 21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT 21-SEP-2011, sequence version 1.
DT 03-AUG-2022, entry version 68.
DE RecName: Full=CBS domain-containing protein CBSCBSPB5;
GN Name=CBSCBSPB5; OrderedLocusNames=At5g50640; ORFNames=MFB16.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19400948; DOI=10.1186/1471-2164-10-200;
RA Kushwaha H.R., Singh A.K., Sopory S.K., Singla-Pareek S.L., Pareek A.;
RT "Genome wide expression analysis of CBS domain containing proteins in
RT Arabidopsis thaliana (L.) Heynh and Oryza sativa L. reveals their
RT developmental and stress regulation.";
RL BMC Genomics 10:200-200(2009).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-18, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AB023037; BAA96977.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95971.1; -; Genomic_DNA.
DR RefSeq; NP_568736.1; NM_124440.3.
DR RefSeq; NP_680412.1; NM_148107.2.
DR AlphaFoldDB; P0DH79; -.
DR SMR; P0DH79; -.
DR iPTMnet; P0DH79; -.
DR PRIDE; P0DH79; -.
DR EnsemblPlants; AT5G50530.1; AT5G50530.1; AT5G50530.
DR EnsemblPlants; AT5G50640.1; AT5G50640.1; AT5G50640.
DR GeneID; 835121; -.
DR GeneID; 835133; -.
DR Gramene; AT5G50530.1; AT5G50530.1; AT5G50530.
DR Gramene; AT5G50640.1; AT5G50640.1; AT5G50640.
DR KEGG; ath:AT5G50530; -.
DR KEGG; ath:AT5G50640; -.
DR Araport; AT5G50640; -.
DR TAIR; locus:2832461; AT5G50640.
DR HOGENOM; CLU_009026_3_0_1; -.
DR InParanoid; P0DH79; -.
DR OMA; KNWGASI; -.
DR OrthoDB; 490251at2759; -.
DR PhylomeDB; P0DH79; -.
DR PRO; PR:P0DH79; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; P0DH79; baseline and differential.
DR Genevisible; P0DH79; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR Gene3D; 3.10.580.10; -; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR034896; CBSCBSPB.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR13780:SF48; PTHR13780:SF48; 1.
DR Pfam; PF00571; CBS; 4.
DR Pfam; PF00564; PB1; 1.
DR SMART; SM00116; CBS; 4.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54631; SSF54631; 2.
DR PROSITE; PS51371; CBS; 4.
DR PROSITE; PS51745; PB1; 1.
PE 1: Evidence at protein level;
KW CBS domain; Membrane; Phosphoprotein; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..548
FT /note="CBS domain-containing protein CBSCBSPB5"
FT /id="PRO_0000412231"
FT TRANSMEM 521..543
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 63..126
FT /note="CBS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 133..190
FT /note="CBS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 233..293
FT /note="CBS 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 301..358
FT /note="CBS 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 411..498
FT /note="PB1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 18
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
SQ SEQUENCE 548 AA; 59812 MW; BD5533B551ADC870 CRC64;
MANQGGPSRK SLSFSGHSFQ GRKKASENEG GGGGGSDLLP RRSLTSSRSS ISLSGERSGE
RTVKRLRLCK ALTVPDSTTL FEACRRMAAR RVDALLLTDS NALLCGILTD RDIATKVIAK
QLNLEETPVS KVMTKNPVFV LSDTIAVEAL QKMVQGKFRH LPVVENGEVI ALLDIAKCLY
DAIARMERSV EKGKAIAAAV EGVEKNWGTS IAGPNTFMET LRERIFKPSL STIIPENTKV
LKVGLDETVL GVTMKMVEYQ SSAAMVMVEN KLVGILTSKD ILMRVISQNL PQETTTVEKV
MTPNPESATV DMAIVEALHI MHNGKFLHLP VLDKDGDVVA VIDVIHITHA AVTTAGSTAG
INNETANSMM QKFWDSAMAL SPNEDGDETR SEEESMKLSS EIEVTKSFSY PNTFAFKLQD
KKGRMHRFMC ETQSLTTLIT AILQRMGDDI EPDNLPQIMY EDEDNDKVVL ASDNDLGAAV
EHAKSIGWKG LKLHLDYTEE RGHRRGLSSE DMDYDQSNSW AAAYKTVAAG AALAAGLGVL
VYLKRNSN
