ID   Y508_MYCBO              Reviewed;         310 AA.
AC   P64716; A0A1R3XWK2; Q11162; X2BF59;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Uncharacterized protein Mb0508;
GN   OrderedLocusNames=BQ2027_MB0508;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.leprae ML2433. {ECO:0000305}.
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DR   EMBL; LT708304; SIT99103.1; -; Genomic_DNA.
DR   RefSeq; NP_854171.1; NC_002945.3.
DR   RefSeq; WP_003402426.1; NC_002945.4.
DR   AlphaFoldDB; P64716; -.
DR   PATRIC; fig|233413.5.peg.553; -.
DR   OMA; YWSEPEP; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..310
FT                   /note="Uncharacterized protein Mb0508"
FT                   /id="PRO_0000103700"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          22..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          178..209
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..142
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        179..193
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   310 AA;  33092 MW;  4954027F694DF5C2 CRC64;
     MTGPHPETES SGNRQISVAE LLARQGVTGA PARRRRRRRG DSDAITVAEL TGEIPIIRDD
     HHHAGPDAHA SQSPAANGRV QVGEAAPQSP AEPVAEQVAE EPTRTVYWSQ PEPRWPKSPP
     QDRRESGPEL SEYPRPLRHT HSDRAPAGPP SGAEHMSPDP VEHYPDLWVD VLDTEVGEAE
     AETEVREAQP GRGERHAAAA AAGTDVEGDG AAEARVARRA LDVVPTLWRG ALVVLQSILA
     VAFGAGLFIA FDQLWRWNSI VALVLSVMVI LGLVVSVRAV RKTEDIASTL IAVAVGALIT
     LGPLALLQSG