ID   Y508_THEMA              Reviewed;         599 AA.
AC   Q9WYX8;
DT   16-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Uncharacterized protein TM_0508;
GN   OrderedLocusNames=TM_0508;
OS   Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS   / MSB8).
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=243274;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8;
RX   PubMed=10360571; DOI=10.1038/20601;
RA   Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA   Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A.,
RA   Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA   Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F.,
RA   Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L.,
RA   Smith H.O., Venter J.C., Fraser C.M.;
RT   "Evidence for lateral gene transfer between Archaea and Bacteria from
RT   genome sequence of Thermotoga maritima.";
RL   Nature 399:323-329(1999).
CC   -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC       family. RarA/MGS1/WRNIP1 subfamily. {ECO:0000305}.
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DR   EMBL; AE000512; AAD35593.1; -; Genomic_DNA.
DR   PIR; B72368; B72368.
DR   RefSeq; NP_228318.1; NC_000853.1.
DR   RefSeq; WP_004081432.1; NZ_CP011107.1.
DR   AlphaFoldDB; Q9WYX8; -.
DR   SMR; Q9WYX8; -.
DR   STRING; 243274.THEMA_02135; -.
DR   EnsemblBacteria; AAD35593; AAD35593; TM_0508.
DR   KEGG; tma:TM0508; -.
DR   eggNOG; COG2110; Bacteria.
DR   eggNOG; COG2256; Bacteria.
DR   InParanoid; Q9WYX8; -.
DR   OMA; RIILSQC; -.
DR   OrthoDB; 166227at2; -.
DR   Proteomes; UP000008183; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008047; F:enzyme activator activity; IBA:GO_Central.
DR   GO; GO:0009378; F:four-way junction helicase activity; IEA:InterPro.
DR   GO; GO:0017116; F:single-stranded DNA helicase activity; IBA:GO_Central.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR   GO; GO:0006282; P:regulation of DNA repair; IBA:GO_Central.
DR   Gene3D; 3.40.220.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR032423; AAA_assoc_2.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   InterPro; IPR021886; MgsA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR008824; RuvB-like_N.
DR   Pfam; PF16193; AAA_assoc_2; 1.
DR   Pfam; PF01661; Macro; 1.
DR   Pfam; PF12002; MgsA_C; 1.
DR   Pfam; PF05496; RuvB_N; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF48019; SSF48019; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF52949; SSF52949; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..599
FT                   /note="Uncharacterized protein TM_0508"
FT                   /id="PRO_0000089221"
FT   DOMAIN          416..599
FT                   /note="Macro"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00490"
FT   BINDING         49..56
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   599 AA;  67418 MW;  B0FB5CB877155BC7 CRC64;
     MSISEKPLSE LLRPKDFEDF VGQDHIFGNK GILRRTLKTG NMFSSILYGP PGSGKTSVFS
     LLKRYFNGEV VYLSSTVHGV SEIKNVLKRG EQLRKYGKKL LLFLDEIHRL NKNQQMVLVS
     HVERGDIVLV ATTTENPSFV IVPALLSRCR ILYFKKLSDE DLMKILKKAT EVLNIDLEES
     VEKAIVRHSE GDARKLLNTL EIVHQAFKNK RVTLEDLETL LGNVSGYTKE SHYDFASAFI
     KSMRGSDPNA AVYYLVKMIE MGEDPRFIAR RMIIFASEDV GLADPNALHI AVSTSIAVEH
     VGLPECLMNL VECAVYLSLA PKSNSVYLAM KKVQELPVED VPLFLRNPVT EEMKKRGYGE
     GYLYPHDFGG FVKTNYLPEK LKNEVIFQPK RVGFEEELFE RLRKLWPEKY GGESMAEVRK
     ELEYKGKKIR IVKGDITREE VDAIVNAANE YLKHGGGVAG AIVRAGGSVI QEESDRIVQE
     RGRVPTGEAV VTSAGKLKAK YVIHTVGPVW RGGSHGEDEL LYKAVYNALL RAHELKLKSI
     SMPAISTGIF GFPKERAVGI FSKAIRDFID QHPDTTLEEI RICNIDEETT KIFEEKFSV