Y5133_ARATH
ID Y5133_ARATH Reviewed; 458 AA.
AC Q9FN67; Q0WL39;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=BTB/POZ domain-containing protein At5g41330;
GN OrderedLocusNames=At5g41330; ORFNames=MYC6.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP DOMAIN BTB.
RX PubMed=15749712; DOI=10.1074/jbc.m413247200;
RA Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L.,
RA Vierstra R.D.;
RT "Cullins 3a and 3b assemble with members of the broad
RT complex/tramtrack/bric-a-brac (BTB) protein family to form essential
RT ubiquitin-protein ligases (E3s) in Arabidopsis.";
RL J. Biol. Chem. 280:18810-18821(2005).
CC -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC ubiquitination and subsequent proteasomal degradation of target
CC proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- DOMAIN: The BTB/POZ domain mediates the interaction with some component
CC of ubiquitin ligase complexes. {ECO:0000269|PubMed:15749712}.
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DR EMBL; AB006707; BAB08505.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94666.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM71072.1; -; Genomic_DNA.
DR EMBL; BT015947; AAV34777.1; -; mRNA.
DR EMBL; AK230358; BAF02157.1; -; mRNA.
DR EMBL; AK230359; BAF02158.1; -; mRNA.
DR EMBL; AK230369; BAF02168.1; -; mRNA.
DR RefSeq; NP_001332628.1; NM_001344398.1.
DR RefSeq; NP_198949.1; NM_123498.2.
DR AlphaFoldDB; Q9FN67; -.
DR STRING; 3702.AT5G41330.1; -.
DR PaxDb; Q9FN67; -.
DR PRIDE; Q9FN67; -.
DR ProteomicsDB; 243130; -.
DR DNASU; 834135; -.
DR EnsemblPlants; AT5G41330.1; AT5G41330.1; AT5G41330.
DR EnsemblPlants; AT5G41330.2; AT5G41330.2; AT5G41330.
DR GeneID; 834135; -.
DR Gramene; AT5G41330.1; AT5G41330.1; AT5G41330.
DR Gramene; AT5G41330.2; AT5G41330.2; AT5G41330.
DR KEGG; ath:AT5G41330; -.
DR Araport; AT5G41330; -.
DR TAIR; locus:2177861; AT5G41330.
DR eggNOG; KOG2714; Eukaryota.
DR HOGENOM; CLU_045194_1_0_1; -.
DR InParanoid; Q9FN67; -.
DR OMA; PGVHLCR; -.
DR OrthoDB; 1064123at2759; -.
DR PhylomeDB; Q9FN67; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9FN67; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FN67; baseline and differential.
DR Genevisible; Q9FN67; AT.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.130.10.10; -; 1.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR045068; BACURD1-3.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR11145; PTHR11145; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF50978; SSF50978; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; Ubl conjugation pathway; WD repeat.
FT CHAIN 1..458
FT /note="BTB/POZ domain-containing protein At5g41330"
FT /id="PRO_0000405332"
FT DOMAIN 11..72
FT /note="BTB"
FT REPEAT 259..305
FT /note="WD 1"
FT REPEAT 360..399
FT /note="WD 2"
FT REPEAT 421..458
FT /note="WD 3"
FT CONFLICT 202
FT /note="N -> T (in Ref. 3; BAF02168)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 458 AA; 50420 MW; 53720DC74C0FD93B CRC64;
MNFPTIPHES NVVSINVGGR IFQTTKQTLS LAGTDSLLSQ LATETTRFVD RDPDLFSVLL
YILRTGNLPA RSRAFDVRDL IDESRYYGIE SFLIDSLSNS SQFEPFDLRR SRILQLNGRD
SPSSISPTVI GGGLHVAHGS KITSFDWSLR QKSTVLTNFS AVDSLLEISP GVLAAGATDF
PGLQIIDLDN GGFVRTTLNW ENVTRSSSTV QAIGSSHEFL FTSFESSRRN SNSIMVYDLS
SLLPVSEIDH CEIYGADIDS AIPSTKLKWI QSCNLLMVSG SHTSPSGVNG HIRFWDVRSR
NMVWEIKEAQ DCFSDVTVSD NLSAVFKVGV TSGEVFYADL RSLGTKDPWV CLGEEKKRNL
NERRGVGSKI ESYGNHVFCS SKGSGIELWS EVITGLVGNA SRDVLEERVF RKNSLGKLAD
SGENKITGLA FGGNRMFVTR KDQQSVQVWQ SPSRGISI
