ID   Y5149_MYCA1             Reviewed;         313 AA.
AC   A0QMX8;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_5149;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_5149;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK68130.1; -; Genomic_DNA.
DR   RefSeq; WP_003874205.1; NC_008595.1.
DR   AlphaFoldDB; A0QMX8; -.
DR   SMR; A0QMX8; -.
DR   EnsemblBacteria; ABK68130; ABK68130; MAV_5149.
DR   KEGG; mav:MAV_5149; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; PMDITEL; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..313
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_5149"
FT                   /id="PRO_0000361116"
FT   BINDING         135
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         164..165
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   313 AA;  34890 MW;  CB4ADA08F371A8FE CRC64;
     MSSLRTHDDT WDIKSSVGTT AVMVAAARAV ETEQPDPLIR DPYAKLLVTN SGAGVLWEAM
     LDPDIAARVE ALDEESAAHL HHMRGYQAVR THFFDTYFAD AVAAGIRQIV ILASGLDSRA
     YRLDWPAGTT VYEIDQPQVL AYKSTTLAEN GVTPSADRRE VAVDLRQDWP AALRAAGFDP
     TQRTAWLAEG LLMYLPAEAQ DRLFTLIGEL SPAGSRVAAE TAPNHADERR QQMRERFKKV
     ADEIGFEQTV DVGELMYRDD HRADVTEWLN AHGWRATAEH STAAMRRLGR WIENVPLADD
     KDAFSDFVVA ERR