ID   Y5150_MYCA1             Reviewed;         313 AA.
AC   A0QMX9;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_5150;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_5150;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK68682.1; -; Genomic_DNA.
DR   RefSeq; WP_009979787.1; NC_008595.1.
DR   AlphaFoldDB; A0QMX9; -.
DR   SMR; A0QMX9; -.
DR   EnsemblBacteria; ABK68682; ABK68682; MAV_5150.
DR   KEGG; mav:MAV_5150; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; QAVRTHY; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..313
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_5150"
FT                   /id="PRO_0000361117"
FT   BINDING         139
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         168..169
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   313 AA;  34068 MW;  642A648154EB082F CRC64;
     MTDLDSSLPP SVRTAGDSWT ITELVGATAL GVAAARAAET AGPDPLIRDE FAGLLVSSAG
     PAWARLADPE QSWLDDDPHG KRAHRVGIDY QAVRTHYFDE YFDGALRAGI RQVVILAAGL
     DSRAYRLNWP AGTTVYEIDQ PKVLEYKTET LQRHGATPAA VRRPVPVDLR DDWPAALTAA
     GFQAARPTAW LAEGLLPYLP SDAQDRLFEM VTALSAAGSQ VAVEVFGMNS RSNAQRWLRM
     RERLGLDVNV AALTYHEPDR SDAAAWLTGH GWRVHSVDNR DEMARLGRPV PEDLSDEAVR
     STLLRAHLGG STG