Y5168_ARATH
ID Y5168_ARATH Reviewed; 359 AA.
AC Q3E8J4; Q9FFR2;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Probably inactive receptor-like protein kinase At5g41680;
GN OrderedLocusNames=At5g41680; ORFNames=MBK23.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT features of the 1.6 Mb regions covered by twenty physically assigned P1
RT clones.";
RL DNA Res. 4:215-230(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-356 (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q3E8J4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q3E8J4-2; Sequence=VSP_038436;
CC -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC inactive. Lacks the conserved Asp active site at position 208, which is
CC replaced by an Asn residue.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
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DR EMBL; AB005233; BAB11474.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94707.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94708.1; -; Genomic_DNA.
DR EMBL; BX832557; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BT029482; ABL66739.1; -; mRNA.
DR RefSeq; NP_198983.2; NM_123532.4. [Q3E8J4-1]
DR RefSeq; NP_974867.1; NM_203138.3. [Q3E8J4-2]
DR AlphaFoldDB; Q3E8J4; -.
DR SMR; Q3E8J4; -.
DR STRING; 3702.AT5G41680.1; -.
DR PaxDb; Q3E8J4; -.
DR PRIDE; Q3E8J4; -.
DR EnsemblPlants; AT5G41680.1; AT5G41680.1; AT5G41680. [Q3E8J4-1]
DR EnsemblPlants; AT5G41680.2; AT5G41680.2; AT5G41680. [Q3E8J4-2]
DR GeneID; 834170; -.
DR Gramene; AT5G41680.1; AT5G41680.1; AT5G41680. [Q3E8J4-1]
DR Gramene; AT5G41680.2; AT5G41680.2; AT5G41680. [Q3E8J4-2]
DR KEGG; ath:AT5G41680; -.
DR Araport; AT5G41680; -.
DR TAIR; locus:2160432; AT5G41680.
DR eggNOG; KOG1187; Eukaryota.
DR InParanoid; Q3E8J4; -.
DR OMA; SSNIFMN; -.
DR OrthoDB; 1102880at2759; -.
DR PhylomeDB; Q3E8J4; -.
DR PRO; PR:Q3E8J4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q3E8J4; baseline and differential.
DR Genevisible; Q3E8J4; AT.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; ATP-binding; Nucleotide-binding; Reference proteome.
FT CHAIN 1..359
FT /note="Probably inactive receptor-like protein kinase
FT At5g41680"
FT /id="PRO_0000389470"
FT DOMAIN 59..357
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 65..73
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 87
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT VAR_SEQ 146..171
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.4"
FT /id="VSP_038436"
SQ SEQUENCE 359 AA; 40290 MW; 8F27AA107DA27A19 CRC64;
MMACCLRNKR RMKGKLSWKS KKRDLSHSGN WAPEDDNDEG KIVFFGGSNY TFDLDDLLAA
SAEILGKGAH VTTYKVAVED TATVVVKRLE EVVVGRREFE QQMEIVGRIR HDNVAELKAY
YYSKIDKLAV YSYYSQGNLF EMLHGKLSFC IPLSMLLWYA VSKTNNSTFA GESQVPLDWE
SRLRIAIGAA RGLAIIHEAD DGKFVHGNIK SSNIFTNSKC YGCICDLGLT HITKSLPQTT
LRSSGYHAPE ITDTRKSTQF SDVYSFGVVL LELLTGKSPA SPLSLDENMD LASWIRSVVS
KEWTGEVFDN ELMMQMGIEE ELVEMLQIGL ACVALKPQDR PHITHIVKLI QDIPTNFNL
