ID   Y516_METST              Reviewed;         234 AA.
AC   Q2NGY8;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=UPF0173 metal-dependent hydrolase Msp_0516 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=Msp_0516;
OS   Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 /
OS   MCB-3).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX   NCBI_TaxID=339860;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3;
RX   PubMed=16385054; DOI=10.1128/jb.188.2.642-658.2006;
RA   Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R.,
RA   Gottschalk G., Thauer R.K.;
RT   "The genome sequence of Methanosphaera stadtmanae reveals why this human
RT   intestinal archaeon is restricted to methanol and H2 for methane formation
RT   and ATP synthesis.";
RL   J. Bacteriol. 188:642-658(2006).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; CP000102; ABC56915.1; -; Genomic_DNA.
DR   RefSeq; WP_011406115.1; NC_007681.1.
DR   AlphaFoldDB; Q2NGY8; -.
DR   SMR; Q2NGY8; -.
DR   STRING; 339860.Msp_0516; -.
DR   EnsemblBacteria; ABC56915; ABC56915; Msp_0516.
DR   GeneID; 41325090; -.
DR   KEGG; mst:Msp_0516; -.
DR   eggNOG; arCOG00497; Archaea.
DR   HOGENOM; CLU_070010_4_0_2; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 76909at2157; -.
DR   Proteomes; UP000001931; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..234
FT                   /note="UPF0173 metal-dependent hydrolase Msp_0516"
FT                   /id="PRO_0000367234"
SQ   SEQUENCE   234 AA;  25395 MW;  11D07A856858555C CRC64;
     MKIEYFGHSA FKIVSEEGLI MLIDPFISNN PLCSTPVETI DADVILITHG HSDHFGDALE
     IANNSGATII ATAEIANFVQ RQGINAIAMN IGGTVSINNL VNVTMTDARH TSSIDFTEEV
     EEGGSATGFV ITLESGKKIY HAGDTGLFGD MKTVIGDIYK PDIALIPIGD KYTMGIEDAA
     IAAKWLQSRI VIPMHYNTFP GIEQDVELFA KNVEDEIIGT MTVPLMPGED YREE