Y5262_ARATH
ID Y5262_ARATH Reviewed; 524 AA.
AC Q6AWW5; Q0WWU3; Q9LZ40;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2004, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Ankyrin repeat-containing protein At5g02620;
GN OrderedLocusNames=At5g02620; ORFNames=T22P11.210;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-508, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. La-0;
RX PubMed=14506206; DOI=10.1074/mcp.t300006-mcp200;
RA Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.;
RT "Large-scale analysis of in vivo phosphorylated membrane proteins by
RT immobilized metal ion affinity chromatography and mass spectrometry.";
RL Mol. Cell. Proteomics 2:1234-1243(2003).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-508, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=15308754; DOI=10.1105/tpc.104.023150;
RA Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.;
RT "Phosphoproteomics of the Arabidopsis plasma membrane and a new
RT phosphorylation site database.";
RL Plant Cell 16:2394-2405(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB85999.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AL162971; CAB85999.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002688; AED90499.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70363.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70366.1; -; Genomic_DNA.
DR EMBL; BT015133; AAT85729.1; -; mRNA.
DR EMBL; BT020220; AAV59286.1; -; mRNA.
DR EMBL; AK226242; BAE98405.1; -; mRNA.
DR PIR; T48283; T48283.
DR RefSeq; NP_001331980.1; NM_001342663.1.
DR RefSeq; NP_001331983.1; NM_001342662.1.
DR RefSeq; NP_195882.2; NM_120340.4.
DR AlphaFoldDB; Q6AWW5; -.
DR SMR; Q6AWW5; -.
DR BioGRID; 17131; 32.
DR IntAct; Q6AWW5; 32.
DR STRING; 3702.AT5G02620.1; -.
DR iPTMnet; Q6AWW5; -.
DR PaxDb; Q6AWW5; -.
DR PRIDE; Q6AWW5; -.
DR ProteomicsDB; 243135; -.
DR EnsemblPlants; AT5G02620.1; AT5G02620.1; AT5G02620.
DR EnsemblPlants; AT5G02620.3; AT5G02620.3; AT5G02620.
DR EnsemblPlants; AT5G02620.4; AT5G02620.4; AT5G02620.
DR GeneID; 831855; -.
DR Gramene; AT5G02620.1; AT5G02620.1; AT5G02620.
DR Gramene; AT5G02620.3; AT5G02620.3; AT5G02620.
DR Gramene; AT5G02620.4; AT5G02620.4; AT5G02620.
DR KEGG; ath:AT5G02620; -.
DR Araport; AT5G02620; -.
DR TAIR; locus:2181768; AT5G02620.
DR eggNOG; KOG0504; Eukaryota.
DR HOGENOM; CLU_000134_49_0_1; -.
DR InParanoid; Q6AWW5; -.
DR OMA; HRIEAYK; -.
DR PhylomeDB; Q6AWW5; -.
DR PRO; PR:Q6AWW5; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q6AWW5; baseline and differential.
DR Genevisible; Q6AWW5; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0008157; F:protein phosphatase 1 binding; IBA:GO_Central.
DR GO; GO:0019888; F:protein phosphatase regulator activity; IBA:GO_Central.
DR GO; GO:0035304; P:regulation of protein dephosphorylation; IBA:GO_Central.
DR Gene3D; 1.25.40.20; -; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR026961; PGG_dom.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF13962; PGG; 1.
DR SMART; SM00248; ANK; 8.
DR SUPFAM; SSF48403; SSF48403; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 6.
PE 1: Evidence at protein level;
KW ANK repeat; Membrane; Phosphoprotein; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..524
FT /note="Ankyrin repeat-containing protein At5g02620"
FT /id="PRO_0000312031"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 441..461
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 472..492
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 16..45
FT /note="ANK 1"
FT REPEAT 55..84
FT /note="ANK 2"
FT REPEAT 90..119
FT /note="ANK 3"
FT REPEAT 124..153
FT /note="ANK 4"
FT REPEAT 158..187
FT /note="ANK 5"
FT REPEAT 192..222
FT /note="ANK 6"
FT REPEAT 226..255
FT /note="ANK 7"
FT REPEAT 260..289
FT /note="ANK 8"
FT MOD_RES 508
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:14506206,
FT ECO:0007744|PubMed:15308754"
FT CONFLICT 417
FT /note="V -> D (in Ref. 4; BAE98405)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 524 AA; 56923 MW; BEA7DD72B8609FE4 CRC64;
MKEIKKTMTK QMTARRDDTP LHTAVREGKT DLLLEMIGEH DGVELKELLA EQNQSGETAL
YVAAEYGYTD MVKILMKHSD SVLAGTKAKN GFDAFHIAAK NGNLQVLDVL IEANPELSFT
FDSSKTTALH TAASQGHGEI VCFLLDKGVD LAAIARSNGK TALHSAARNG HTVIVKKLIE
KKAGMVTRVD KKGQTALHMA VKGQNTEIVD VLMEADGSLI NSADNKGNTP LHIAVRKNRA
EIVQTVLKYC EVSRVAVNKS GETALDIAEK TGLHEIVPLL QKIGMQNARS IKPAEKVEPS
GSSRKLKETV SEIGHEVHTQ LEQTGRTRRE IQGIAKRVNK MHTEGLNNAI NSTTLVAILI
ATVAFAAIFN VPGQYTDDPK DVPPGYSLGE ARAAPRPEFL IFVVFDSFAL FISLAVVVVQ
TSVVVIERRA KKQMMAIINK LMWMACIMIS VAFVSLSFVV VGEKEKPLAV GVTAIGALIM
VSTLGTMCYW VIANRIEGSK SSPASMMSDP ELADSKHNRK LYAV
