Y5279_ARATH
ID Y5279_ARATH Reviewed; 500 AA.
AC Q9LTD8; F4KHM3;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=DUF21 domain-containing protein At5g52790;
DE AltName: Full=CBS domain-containing protein CBSDUF5;
GN Name=CBSDUF5; OrderedLocusNames=At5g52790; ORFNames=F6N7.28;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19400948; DOI=10.1186/1471-2164-10-200;
RA Kushwaha H.R., Singh A.K., Sopory S.K., Singla-Pareek S.L., Pareek A.;
RT "Genome wide expression analysis of CBS domain containing proteins in
RT Arabidopsis thaliana (L.) Heynh and Oryza sativa L. reveals their
RT developmental and stress regulation.";
RL BMC Genomics 10:200-200(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA98097.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BX831668; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AB025606; BAA98097.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED96260.1; -; Genomic_DNA.
DR EMBL; BX831668; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_200091.2; NM_124657.3.
DR AlphaFoldDB; Q9LTD8; -.
DR SMR; Q9LTD8; -.
DR STRING; 3702.AT5G52790.1; -.
DR PaxDb; Q9LTD8; -.
DR PRIDE; Q9LTD8; -.
DR EnsemblPlants; AT5G52790.1; AT5G52790.1; AT5G52790.
DR GeneID; 835356; -.
DR Gramene; AT5G52790.1; AT5G52790.1; AT5G52790.
DR KEGG; ath:AT5G52790; -.
DR Araport; AT5G52790; -.
DR TAIR; locus:2149659; AT5G52790.
DR eggNOG; KOG2118; Eukaryota.
DR HOGENOM; CLU_011310_0_0_1; -.
DR InParanoid; Q9LTD8; -.
DR OrthoDB; 1446644at2759; -.
DR PRO; PR:Q9LTD8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LTD8; baseline and differential.
DR Genevisible; Q9LTD8; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; -; 2.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064; PTHR12064; 1.
DR Pfam; PF01595; DUF21; 1.
DR SUPFAM; SSF54631; SSF54631; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 2: Evidence at transcript level;
KW CBS domain; Glycoprotein; Membrane; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..500
FT /note="DUF21 domain-containing protein At5g52790"
FT /id="PRO_0000411682"
FT TOPO_DOM 1..12
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 34..71
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 93..95
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 117..137
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 159..500
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT DOMAIN 9..192
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01193"
FT DOMAIN 211..275
FT /note="CBS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 276..319
FT /note="CBS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 326..386
FT /note="CBS 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT CARBOHYD 311
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 342
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 316
FT /note="N -> K (in Ref. 3; BX831668)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 500 AA; 55127 MW; F2E9D297842587EC CRC64;
MAANDVPCCE TMFWVYLLVC VALVVFAGLM SGLTLGLMSL SIVELEVMIK AGEPHDRKNA
EKILPLVKNQ HLLLCTLLIG NALAMEALPI FVDSLLPAWG AILISVTLIL AFGEIIPQAV
CSRYGLSIGA KLSFLVRLII IVFFPLSYPI SKLLDLLLGK RHSTLLGRAE LKSLVYMHGN
EAGKGGELTH DETTIISGAL DMSQKSAKDA MTPVSQIFSL DINFKLDEKT MGLIASAGHS
RIPIYSVNPN VIIGFILVKN LIKVRPEDET SIRDLPIRRM PKVDLNLPLY DILNIFQTGR
SHMAAVVGTK NHTNTNTPVH EKSINGSPNK DANVFLSIPA LNSSETSHQS PIRYIDSISD
EDEEVIGIIT LEDVMEELIQ EEIYDETDQY VELHKRITIN MPMSGNSPET ATWASELASP
ISPYRSSLLS PSIMISTLLR SPINSPYRHS LLLRPTLHAS PPAQSPSILS PDSNNERYYY
LSPSRVLRKS YEKLSRSNGS
