Y5285_ARATH
ID Y5285_ARATH Reviewed; 254 AA.
AC Q8GYK7; Q9LYA1;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=TLC domain-containing protein At5g14285 {ECO:0000305};
GN OrderedLocusNames=At5g14285 {ECO:0000312|Araport:AT5G14285};
GN ORFNames=F18O22_70 {ECO:0000312|EMBL:CAB87767.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Seki M., Iida K., Satou M., Sakurai T., Akiyama K., Ishida J., Nakajima M.,
RA Enju A., Kamiya A., Narusaka M., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Arabidopsis thaliana full-length cDNA.";
RL Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB87767.1; Type=Erroneous gene model prediction; Note=The predicted gene At5g14280 has been split into 2 genes: At5g14280 and At5g14285.; Evidence={ECO:0000305};
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DR EMBL; AL163817; CAB87767.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; ANM69535.1; -; Genomic_DNA.
DR EMBL; AK117548; BAC42209.1; -; mRNA.
DR PIR; T48601; T48601.
DR RefSeq; NP_001331205.1; NM_001343332.1.
DR AlphaFoldDB; Q8GYK7; -.
DR SMR; Q8GYK7; -.
DR STRING; 3702.AT5G14280.1; -.
DR PRIDE; Q8GYK7; -.
DR ProteomicsDB; 243014; -.
DR EnsemblPlants; AT5G14285.1; AT5G14285.1; AT5G14285.
DR GeneID; 28721155; -.
DR Gramene; AT5G14285.1; AT5G14285.1; AT5G14285.
DR KEGG; ath:AT5G14285; -.
DR Araport; AT5G14285; -.
DR OMA; WVWVSWI; -.
DR OrthoDB; 1172548at2759; -.
DR PRO; PR:Q8GYK7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8GYK7; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR040327; At5g14285-like.
DR InterPro; IPR006634; TLC-dom.
DR PANTHER; PTHR31766; PTHR31766; 1.
DR Pfam; PF03798; TRAM_LAG1_CLN8; 1.
DR SMART; SM00724; TLC; 1.
DR PROSITE; PS50922; TLC; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..254
FT /note="TLC domain-containing protein At5g14285"
FT /id="PRO_0000436974"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 38..248
FT /note="TLC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00205"
SQ SEQUENCE 254 AA; 28600 MW; 8A1BC65B26E90A4C CRC64;
MSINIGEISI PDLPIFFSMF LTIYLIAYFI VFRNWKPQIR PEASSCLISI FHGSPAVFLA
TRAVFSSSER SFASANTAAQ NTVLDFSVAY FLTDLFHYIV FNPNDVLFIG HHVATLFVFL
TCRFLVFHGA CAILGLLILA EVTSACQNAW TLAGARKNDP ESRLAVKVYD LLSPPFYAFY
SIVRGVLGPL FFGKMVAFYA RGGAHGVIPN WLWISWAIVV GIAITVSILW IWNLWIELFS
ERKANKIRVD KKIR
