Y528_STAES
ID Y528_STAES Reviewed; 356 AA.
AC Q8CTF5;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=Uncharacterized membrane protein SE_0528;
GN OrderedLocusNames=SE_0528;
OS Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=176280;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12228 / FDA PCI 1200;
RX PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT "Genome-based analysis of virulence genes in a non-biofilm-forming
RT Staphylococcus epidermidis strain (ATCC 12228).";
RL Mol. Microbiol. 49:1577-1593(2003).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AE015929; AAO04125.1; -; Genomic_DNA.
DR RefSeq; NP_764083.1; NC_004461.1.
DR RefSeq; WP_002494710.1; NZ_WBME01000015.1.
DR AlphaFoldDB; Q8CTF5; -.
DR SMR; Q8CTF5; -.
DR STRING; 176280.SE_0528; -.
DR EnsemblBacteria; AAO04125; AAO04125; SE_0528.
DR GeneID; 50019324; -.
DR KEGG; sep:SE_0528; -.
DR PATRIC; fig|176280.10.peg.500; -.
DR eggNOG; COG2199; Bacteria.
DR HOGENOM; CLU_000445_11_1_9; -.
DR OMA; FKQYKFQ; -.
DR Proteomes; UP000001411; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; SSF55073; 1.
DR TIGRFAMs; TIGR00254; GGDEF; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..356
FT /note="Uncharacterized membrane protein SE_0528"
FT /id="PRO_0000286961"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 218..353
FT /note="GGDEF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00095"
SQ SEQUENCE 356 AA; 40592 MW; A33CA6106ED8F202 CRC64;
MFEAIIYNIS VMVAGIYLFH RLQYSENKRM IFSKEYVTVL MTFVSLLLAA YPIPFQNEYL
VHLTFVPLLF LGRYTNMIYT LTAAFIVSLV DVFIFGNSII YGITLIVIAG IVSAVGPFLK
QNDIISLLIL NLISIIILLF LALLSPIYEL VEILVLIPIS FIITIASAIT FVDIWHFFSL
VNRYENEDKY DYLTGLGNVK EFDRHLNEVS SKAEEKKQSL ALLLIDIDGF KDVNDHYSHQ
SGDAVLKQMS QLLKNYVPNQ FKIFRNGGEE FSVVIRDYTL DQSVKLAENI RSGVEKSSFH
LPNKEVIKLS VSIGVGYLTQ EDRKSQRKVF KDADDMVHVA KSEGRNKVMF NPIVKL
