Y5332_ARATH
ID Y5332_ARATH Reviewed; 601 AA.
AC Q9FK10; Q0WUK3;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Probable inactive receptor kinase At5g53320;
DE Flags: Precursor;
GN OrderedLocusNames=At5g53320; ORFNames=K19E1.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- INTERACTION:
CC Q9FK10; F4I065: At1g49100; NbExp=2; IntAct=EBI-20654730, EBI-20654598;
CC Q9FK10; A0A178WLG7: At1g51790; NbExp=2; IntAct=EBI-20654730, EBI-20652336;
CC Q9FK10; A0A1P8ASI5: At1g56120; NbExp=3; IntAct=EBI-20654730, EBI-20656718;
CC Q9FK10; O64556: At2g19230; NbExp=4; IntAct=EBI-20654730, EBI-20662335;
CC Q9FK10; Q9LIG2: At3g21340; NbExp=2; IntAct=EBI-20654730, EBI-941096;
CC Q9FK10; Q9SNA2: F18L15.70; NbExp=3; IntAct=EBI-20654730, EBI-20658889;
CC Q9FK10; C0LGU0: PRK1; NbExp=2; IntAct=EBI-20654730, EBI-20665360;
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC inactive.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. {ECO:0000305}.
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DR EMBL; AB013388; BAB09794.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96339.1; -; Genomic_DNA.
DR EMBL; AK227151; BAE99195.1; -; mRNA.
DR RefSeq; NP_200144.1; NM_124711.4.
DR AlphaFoldDB; Q9FK10; -.
DR SMR; Q9FK10; -.
DR BioGRID; 20658; 40.
DR IntAct; Q9FK10; 46.
DR STRING; 3702.AT5G53320.1; -.
DR iPTMnet; Q9FK10; -.
DR PaxDb; Q9FK10; -.
DR PRIDE; Q9FK10; -.
DR ProteomicsDB; 243159; -.
DR EnsemblPlants; AT5G53320.1; AT5G53320.1; AT5G53320.
DR GeneID; 835413; -.
DR Gramene; AT5G53320.1; AT5G53320.1; AT5G53320.
DR KEGG; ath:AT5G53320; -.
DR Araport; AT5G53320; -.
DR TAIR; locus:2154227; AT5G53320.
DR eggNOG; ENOG502QTFK; Eukaryota.
DR HOGENOM; CLU_000288_92_6_1; -.
DR InParanoid; Q9FK10; -.
DR OMA; SICTKWT; -.
DR OrthoDB; 826997at2759; -.
DR PhylomeDB; Q9FK10; -.
DR PRO; PR:Q9FK10; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FK10; baseline and differential.
DR Genevisible; Q9FK10; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR Pfam; PF00560; LRR_1; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Leucine-rich repeat; Membrane; Nucleotide-binding;
KW Phosphoprotein; Receptor; Reference proteome; Repeat; Signal;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..601
FT /note="Probable inactive receptor kinase At5g53320"
FT /id="PRO_0000324842"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 91..114
FT /note="LRR 1"
FT REPEAT 115..136
FT /note="LRR 2"
FT REPEAT 139..161
FT /note="LRR 3"
FT REPEAT 163..184
FT /note="LRR 4"
FT REPEAT 185..206
FT /note="LRR 5"
FT DOMAIN 308..569
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 314..322
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 336
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT MOD_RES 310
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q94F62"
FT MOD_RES 387
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q94AG2"
FT MOD_RES 408
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q94AG2"
FT MOD_RES 478
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q94AG2"
FT MOD_RES 549
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q94AG2"
FT CONFLICT 88
FT /note="R -> S (in Ref. 3; BAE99195)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 601 AA; 66863 MW; 4709B340F97DC4DE CRC64;
MKCQVVLILI VVIFNVCIEA ETIKEDKHTL LQFVNNINHS HSLNWSPSLS ICTKWTGVTC
NSDHSSVDAL HLAATGLRGD IELSIIARLS NLRFLILSSN NISGTFPTTL QALKNLTELK
LDFNEFSGPL PSDLSSWERL QVLDLSNNRF NGSIPSSIGK LTLLHSLNLA YNKFSGEIPD
LHIPGLKLLN LAHNNLTGTV PQSLQRFPLS AFVGNKVLAP VHSSLRKHTK HHNHVVLGIA
LSVCFAILAL LAILLVIIIH NREEQRRSSK DKPSKRRKDS DPNVGEGDNK IVFFEGKNLV
FDLEDLLRAS AEVLGKGPFG TTYKVDLEDS ATIVVKRIKE VSVPQREFEQ QIENIGSIKH
ENVATLRGYF YSKDEKLVVY DYYEHGSLST LLHGQKGLRD RKRLEWETRL NMVYGTARGV
AHIHSQSGGK LVHGNIKSSN IFLNGKGYGC ISGTGMATLM HSLPRHAVGY RAPEITDTRK
GTQPSDVYSF GILIFEVLTG KSEVANLVRW VNSVVREEWT GEVFDEELLR CTQVEEEMVE
MLQVGMVCTA RLPEKRPNMI EVVRMVEEIR PEKLASGYRS EVSTGATTTP IGSLSGSPYI
L
