Y5349_ARATH
ID Y5349_ARATH Reviewed; 543 AA.
AC Q9FMV3; Q0WMA2;
DT 21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=CBS domain-containing protein CBSCBSPB1;
GN Name=CBSCBSPB1; OrderedLocusNames=At5g63490; ORFNames=MLE2.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9501997; DOI=10.1093/dnares/4.6.401;
RA Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence
RT features of the regions of 1,191,918 bp covered by seventeen physically
RT assigned P1 clones.";
RL DNA Res. 4:401-414(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19400948; DOI=10.1186/1471-2164-10-200;
RA Kushwaha H.R., Singh A.K., Sopory S.K., Singla-Pareek S.L., Pareek A.;
RT "Genome wide expression analysis of CBS domain containing proteins in
RT Arabidopsis thaliana (L.) Heynh and Oryza sativa L. reveals their
RT developmental and stress regulation.";
RL BMC Genomics 10:200-200(2009).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AB007649; BAB08814.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97758.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM69496.1; -; Genomic_DNA.
DR EMBL; AK228838; BAF00733.1; -; mRNA.
DR EMBL; AK229928; BAF01754.1; -; mRNA.
DR RefSeq; NP_001331166.1; NM_001345594.1.
DR RefSeq; NP_201154.1; NM_125744.3.
DR AlphaFoldDB; Q9FMV3; -.
DR SMR; Q9FMV3; -.
DR STRING; 3702.AT5G63490.1; -.
DR iPTMnet; Q9FMV3; -.
DR PaxDb; Q9FMV3; -.
DR PRIDE; Q9FMV3; -.
DR ProteomicsDB; 243136; -.
DR EnsemblPlants; AT5G63490.1; AT5G63490.1; AT5G63490.
DR EnsemblPlants; AT5G63490.2; AT5G63490.2; AT5G63490.
DR GeneID; 836468; -.
DR Gramene; AT5G63490.1; AT5G63490.1; AT5G63490.
DR Gramene; AT5G63490.2; AT5G63490.2; AT5G63490.
DR KEGG; ath:AT5G63490; -.
DR Araport; AT5G63490; -.
DR TAIR; locus:2167331; AT5G63490.
DR eggNOG; ENOG502QVK2; Eukaryota.
DR HOGENOM; CLU_009026_3_0_1; -.
DR InParanoid; Q9FMV3; -.
DR OMA; DMSIQSA; -.
DR OrthoDB; 490251at2759; -.
DR PhylomeDB; Q9FMV3; -.
DR PRO; PR:Q9FMV3; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FMV3; baseline and differential.
DR Genevisible; Q9FMV3; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.580.10; -; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR034896; CBSCBSPB.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR13780:SF129; PTHR13780:SF129; 1.
DR Pfam; PF00571; CBS; 4.
DR Pfam; PF00564; PB1; 1.
DR SMART; SM00116; CBS; 4.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54631; SSF54631; 2.
DR PROSITE; PS51371; CBS; 4.
DR PROSITE; PS51745; PB1; 1.
PE 1: Evidence at protein level;
KW CBS domain; Membrane; Phosphoprotein; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..543
FT /note="CBS domain-containing protein CBSCBSPB1"
FT /id="PRO_0000412227"
FT TRANSMEM 518..538
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 59..118
FT /note="CBS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 125..183
FT /note="CBS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 225..285
FT /note="CBS 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 293..350
FT /note="CBS 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 402..489
FT /note="PB1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 17
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q0WLC7"
SQ SEQUENCE 543 AA; 59435 MW; E403577EF055CE45 CRC64;
MASQGGPRRS LSVTTASLHG KKKSMDMAER GLDTGRRSLT VSRSPLGLTG GERTVKRLRL
SKALTVPATT TIYEACKRMA SRRVDALLLT DSNEMLCGIL TDKDIATRVI SQELNVEETP
VSKVMTKNPM FVLSETLAVE ALQKMVQGKF RHLPVVENGE VIALLDIAKC LYDAIARMER
AAEKGKAIAA AVEGVEKSWG TNTSVPNTFI ETLRDRMFRP SLSTIIPDDT KVLKVSPTDT
VLTVAKKMVE FQSSCAVVII EDKLRGIFTS KDILMRVVAE NLPPSETLVE TVMTQNPEST
IVDTPIVEAL HIMHEGKFLH LPVTDKEGDV VAVVDVIHVT HAAVATAGTT AGIGNEATNT
MMQKFWDSAM ALSPNEDDED SRSESSMKVA SEAETGKSFP FANTFSFKIE DKKHRKHRFI
SDTRSLTEVI TAIIQRVGDD IDPDNFPQIL YEDEDHDKVL LASDSDLQAA IEHAKSIGWK
SLRLHLDDSR EGKGRRRRRA SGSAESMEYV ETDAWAAAYS GVAAGAALVA GLGFMAFLRK
FGH
