ID   Y535_PYRFU              Reviewed;         142 AA.
AC   Q8U3D3;
DT   28-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Putative transcriptional regulatory protein PF0535 {ECO:0000255|HAMAP-Rule:MF_00620};
GN   OrderedLocusNames=PF0535;
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX   PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
CC   -!- FUNCTION: Putative transcriptional regulator. {ECO:0000255|HAMAP-
CC       Rule:MF_00620}.
CC   -!- SIMILARITY: Belongs to the Tfx family. {ECO:0000255|HAMAP-
CC       Rule:MF_00620}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE009950; AAL80659.1; -; Genomic_DNA.
DR   RefSeq; WP_011011652.1; NZ_CP023154.1.
DR   AlphaFoldDB; Q8U3D3; -.
DR   SMR; Q8U3D3; -.
DR   STRING; 186497.PF0535; -.
DR   PRIDE; Q8U3D3; -.
DR   EnsemblBacteria; AAL80659; AAL80659; PF0535.
DR   GeneID; 41712337; -.
DR   KEGG; pfu:PF0535; -.
DR   PATRIC; fig|186497.12.peg.559; -.
DR   eggNOG; arCOG04554; Archaea.
DR   HOGENOM; CLU_125807_0_1_2; -.
DR   OMA; VKVPYST; -.
DR   OrthoDB; 96651at2157; -.
DR   PhylomeDB; Q8U3D3; -.
DR   Proteomes; UP000001013; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 3.30.1190.10; -; 1.
DR   HAMAP; MF_00620; HTH_type_Tfx; 1.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR029291; Tfx_C.
DR   InterPro; IPR004645; Tfx_DNA-bd_arc.
DR   InterPro; IPR018384; Tfx_DNA-bd_euryarc.
DR   InterPro; IPR036657; Tfx_DNA-bd_sf_arc.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   Pfam; PF14601; TFX_C; 1.
DR   PIRSF; PIRSF004932; DNA_bind_Tfx; 1.
DR   SUPFAM; SSF89915; SSF89915; 1.
DR   TIGRFAMs; TIGR00721; tfx; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..142
FT                   /note="Putative transcriptional regulatory protein PF0535"
FT                   /id="PRO_0000144173"
SQ   SEQUENCE   142 AA;  16310 MW;  1BDACC51CFB6C7F5 CRC64;
     MKTFLTEQQI KVLMLRAKGY KQSEIAKILG TSRANVSILE KRAMEKIEKA RNTLLLWEQI
     NSKVIVEIKA GEDIFSIPEK FFKKADKVGV KVPYSTAEII TFLVEHAPVE DRLAKRDFVL
     FLDSKNKLRI GDCLVIEEIK ED