ID   Y535_SACS2              Reviewed;         350 AA.
AC   Q9UWU0;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=UPF0219 protein SSO0535 {ECO:0000255|HAMAP-Rule:MF_01409};
GN   OrderedLocusNames=SSO0535; ORFNames=C22_016;
OS   Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
OS   (Sulfolobus solfataricus).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Saccharolobus.
OX   NCBI_TaxID=273057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
RX   PubMed=10701121; DOI=10.1139/g99-108;
RA   Charlebois R.L., Singh R.K., Chan-Weiher C.C.-Y., Allard G., Chow C.,
RA   Confalonieri F., Curtis B., Duguet M., Erauso G., Faguy D., Gaasterland T.,
RA   Garrett R.A., Gordon P., Jeffries A.C., Kozera C., Kushwaha N., Lafleur E.,
RA   Medina N., Peng X., Penny S.L., She Q., St Jean A., van der Oost J.,
RA   Young F., Zivanovic Y., Doolittle W.F., Ragan M.A., Sensen C.W.;
RT   "Gene content and organization of a 281-kbp contig from the genome of the
RT   extremely thermophilic archaeon, Sulfolobus solfataricus P2.";
RL   Genome 43:116-136(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
RX   PubMed=11427726; DOI=10.1073/pnas.141222098;
RA   She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J.,
RA   Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G.,
RA   Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J.,
RA   Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C.,
RA   Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T.,
RA   Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
RT   "The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. UPF0219 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01409}.
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DR   EMBL; Y18930; CAB57764.1; -; Genomic_DNA.
DR   EMBL; AE006641; AAK40854.1; -; Genomic_DNA.
DR   PIR; G90199; G90199.
DR   RefSeq; WP_009991040.1; NC_002754.1.
DR   AlphaFoldDB; Q9UWU0; -.
DR   SMR; Q9UWU0; -.
DR   STRING; 273057.SSO0535; -.
DR   EnsemblBacteria; AAK40854; AAK40854; SSO0535.
DR   GeneID; 44129544; -.
DR   KEGG; sso:SSO0535; -.
DR   PATRIC; fig|273057.12.peg.533; -.
DR   eggNOG; arCOG01767; Archaea.
DR   HOGENOM; CLU_039592_7_0_2; -.
DR   InParanoid; Q9UWU0; -.
DR   OMA; YAKHKGK; -.
DR   PhylomeDB; Q9UWU0; -.
DR   Proteomes; UP000001974; Chromosome.
DR   GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR   GO; GO:0004421; F:hydroxymethylglutaryl-CoA synthase activity; IBA:GO_Central.
DR   GO; GO:0006084; P:acetyl-CoA metabolic process; IBA:GO_Central.
DR   GO; GO:0010142; P:farnesyl diphosphate biosynthetic process, mevalonate pathway; IBA:GO_Central.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 1.
DR   HAMAP; MF_01409; UPF0219; 1.
DR   InterPro; IPR013751; ACP_syn_III.
DR   InterPro; IPR013747; ACP_syn_III_C.
DR   InterPro; IPR004656; FabH-rel.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF08545; ACP_syn_III; 1.
DR   Pfam; PF08541; ACP_syn_III_C; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR00748; HMG_CoA_syn_Arc; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..350
FT                   /note="UPF0219 protein SSO0535"
FT                   /id="PRO_0000057625"
SQ   SEQUENCE   350 AA;  37923 MW;  A0840A9CCB57B0DF CRC64;
     MLSGILGWGA YIPRYRIKVE DIAKMWGYDE AVVKSLGLTE KSVPGHDEDS TTIAWESSIN
     AIKRAQVDTS KIRLVLFGSE SKVYAVKPTS TILIDALGIN NYSATADMEF ACRAASVGLR
     LASSFVLHNN DSYALVIGAD TAQSNPGDVL ELSSAAAGVA FVVGKTDEKH SAAVIEYSSS
     YTSDTPDFWR RDGTPYPVHG EGFTGEPAYF HHIISAVNDL LQNSGLKISD FDYFVFHQPN
     GKFPIQVAKK LGVPLEKVKQ GLVSPYIGNP YNASALLGLA KVLDIAKPGE RILVAPFGSG
     AGSDAFSILV SEGILAKQKL AKTVEYYINN KKLVSYAEYA KYTNKIKVYE