ID   Y5360_ARATH             Reviewed;         591 AA.
AC   Q9FNB3;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Putative BTB/POZ domain-containing protein At5g13600;
GN   OrderedLocusNames=At5g13600; ORFNames=T6I14.9;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA   Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT   features of the regions of 1,044,062 bp covered by thirteen physically
RT   assigned P1 clones.";
RL   DNA Res. 4:291-300(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   DOMAIN BTB.
RX   PubMed=15749712; DOI=10.1074/jbc.m413247200;
RA   Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L.,
RA   Vierstra R.D.;
RT   "Cullins 3a and 3b assemble with members of the broad
RT   complex/tramtrack/bric-a-brac (BTB) protein family to form essential
RT   ubiquitin-protein ligases (E3s) in Arabidopsis.";
RL   J. Biol. Chem. 280:18810-18821(2005).
CC   -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC       protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC       ubiquitination and subsequent proteasomal degradation of target
CC       proteins. {ECO:0000250}.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- DOMAIN: The BTB/POZ domain mediates the interaction with some component
CC       of ubiquitin ligase complexes. {ECO:0000269|PubMed:15749712}.
CC   -!- SIMILARITY: Belongs to the NPH3 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00982}.
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DR   EMBL; AB006704; BAB08686.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED91916.1; -; Genomic_DNA.
DR   RefSeq; NP_196864.1; NM_121363.1.
DR   AlphaFoldDB; Q9FNB3; -.
DR   SMR; Q9FNB3; -.
DR   PaxDb; Q9FNB3; -.
DR   PRIDE; Q9FNB3; -.
DR   ProteomicsDB; 243110; -.
DR   EnsemblPlants; AT5G13600.1; AT5G13600.1; AT5G13600.
DR   GeneID; 831204; -.
DR   Gramene; AT5G13600.1; AT5G13600.1; AT5G13600.
DR   KEGG; ath:AT5G13600; -.
DR   Araport; AT5G13600; -.
DR   TAIR; locus:2173204; AT5G13600.
DR   eggNOG; ENOG502QR2D; Eukaryota.
DR   HOGENOM; CLU_005994_3_1_1; -.
DR   InParanoid; Q9FNB3; -.
DR   OMA; HWLTDSE; -.
DR   OrthoDB; 481589at2759; -.
DR   PhylomeDB; Q9FNB3; -.
DR   UniPathway; UPA00143; -.
DR   PRO; PR:Q9FNB3; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FNB3; baseline and differential.
DR   Genevisible; Q9FNB3; AT.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR043454; NPH3/RPT2-like.
DR   InterPro; IPR027356; NPH3_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR32370; PTHR32370; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF03000; NPH3; 1.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
DR   PROSITE; PS51649; NPH3; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..591
FT                   /note="Putative BTB/POZ domain-containing protein
FT                   At5g13600"
FT                   /id="PRO_0000409583"
FT   DOMAIN          28..95
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   DOMAIN          208..493
FT                   /note="NPH3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00982"
FT   MOD_RES         434
FT                   /note="Phosphotyrosine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9FMF5"
SQ   SEQUENCE   591 AA;  66500 MW;  D98DFD6279C2C3CC CRC64;
     MASLKLGSKS EVFHLSGHTW LCKTGLKPDV MIQVVDESFH LHKFPLLSRS GYLETLFSKA
     SETTCVAQLH DIPGGPETFL LVAKFCYGVR IEVTPENAVS LRCAAEYLQM SENYGDANLI
     YLTESFLNDH VFVNWEDSIK ALEKSCEPKV LPLAEELHIV SRCIGSLAMK ACAEDNTSFF
     NWPISLPEGT TTTTIYWNGI QTKATSENWW FNDVSSFLDL PMYKRFIKTV ESRGVNAGII
     AASVTHYAKR NLPLLGCSRK SGSPSEEGTN YGDDMYYSHE EQRSLLEEIV ELLPGKKCVT
     STKFLLRLLR TSMVLHASQV TQETLEKRIG MQLDEAALED LLIPNMKYSG ETLYDTDSVQ
     RILDHFMLTF DSSIVEEKQM MGDSHPLKSI TKVASLIDGY LAEVASDENL KLSKFQALGA
     LIPEDVRPMD DGIYRAIDIY IKAHPWLTES EREQLCLLMN CQKLSLEACT HAAQNERLPL
     RVIVQVLFFE QMRLRTSIAG WLFGSEENND TSGALEGNKN TNANMVMHGM RERVFELEKE
     CMSMKQDLDK LVKTKEGRNF FSKIFGSRSK TKTSPCGKGG EDALVIPETK N