Y5393_ARATH
ID Y5393_ARATH Reviewed; 806 AA.
AC Q9FID5;
DT 13-OCT-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Probable receptor-like protein kinase At5g39030;
DE EC=2.7.11.-;
DE Flags: Precursor;
GN OrderedLocusNames=At5g39030; ORFNames=MXF12.40;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=19529822; DOI=10.1093/mp/ssn083;
RA Chae L., Sudat S., Dudoit S., Zhu T., Luan S.;
RT "Diverse transcriptional programs associated with environmental stress and
RT hormones in the Arabidopsis receptor-like kinase gene family.";
RL Mol. Plant 2:84-107(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
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DR EMBL; AB016892; BAB10827.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94389.1; -; Genomic_DNA.
DR RefSeq; NP_198719.1; NM_123265.2.
DR AlphaFoldDB; Q9FID5; -.
DR SMR; Q9FID5; -.
DR STRING; 3702.AT5G39030.1; -.
DR PaxDb; Q9FID5; -.
DR PRIDE; Q9FID5; -.
DR EnsemblPlants; AT5G39030.1; AT5G39030.1; AT5G39030.
DR GeneID; 833895; -.
DR Gramene; AT5G39030.1; AT5G39030.1; AT5G39030.
DR KEGG; ath:AT5G39030; -.
DR Araport; AT5G39030; -.
DR TAIR; locus:2177152; AT5G39030.
DR eggNOG; KOG1187; Eukaryota.
DR HOGENOM; CLU_000288_42_5_1; -.
DR InParanoid; Q9FID5; -.
DR OrthoDB; 403686at2759; -.
DR PhylomeDB; Q9FID5; -.
DR PRO; PR:Q9FID5; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FID5; baseline and differential.
DR Genevisible; Q9FID5; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR GO; GO:0010038; P:response to metal ion; IGI:TAIR.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR045874; LRK10-like.
DR InterPro; IPR024788; Malectin-like_Carb-bd_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27009; PTHR27009; 1.
DR Pfam; PF12819; Malectin_like; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Glycoprotein; Kinase; Membrane; Nucleotide-binding;
KW Reference proteome; Serine/threonine-protein kinase; Signal; Transferase;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..806
FT /note="Probable receptor-like protein kinase At5g39030"
FT /id="PRO_0000386562"
FT TOPO_DOM 18..443
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 444..464
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 465..806
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 498..775
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT ACT_SITE 621
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT ECO:0000255|PROSITE-ProRule:PRU10027"
FT BINDING 504..512
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 526
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT CARBOHYD 59
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 134
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 164
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 171
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 212
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 233
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 261
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 297
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 401
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 806 AA; 90671 MW; A4F516AE13228D79 CRC64;
MICFILFVFS FLVSVSATAP YKPDDVFLIN CGETDVPFDN HGRTWTQEEK NILPKNSDNA
SFSSVVSYKE ESGIPQVPYM TARIFRSDFT YSFPVSPGWK FLRLYFYPTS YKSGFDAVNS
FVSVTVNDFT LLQNFSADLT VKASIPESKS LIKEFIVPVY LTLNLTFRPS NNSLAFVNGI
EIVSMPDRFY SKGGFDDLIT NVGSLIDFEI DNSTASETVH RLNVGGHMVD EVNDSGMFRR
WLSDDYEFLI GGVSPYMPDV NISYTEKTPA YVAPAYVYST CRMMGNAQDT YLNLNFNLTW
LFTVDAGFSY LVRLHFFEKY LNKANQRVFS IFLGNQMARE EMDVIRLSGG PRIPIYLDFR
IYVGSESGPR PDLRLDLHPL VKDNPEYYEA ILNGVEILKL NNSGNLAIIQ DNELKPNPPL
SSNLTPNHVT QQIKGKSSHL LVKIFIAVGP GTGLATFVVV LMLWMRQMKR KNRKEERVVM
FKKLLNMYTY AELKKITKSF SYIIGKGGFG TVYGGNLSNG RKVAVKVLKD LKGSAEDFIN
EVASMSQTSH VNIVSLLGFC FEGSKRAIVY EFLENGSLDQ FMSRNKSLTQ DVTTLYGIAL
GIARGLEYLH YGCKTRIVHF DIKPQNILLD GNLCPKVSDF GLAKLCEKRE SVLSLMDTRG
TIGYIAPEVF SRMYGRVSHK SDVYSFGMLV IDMIGARSKE IVETVDSAAS STYFPDWIYK
DLEDGEQTWI FGDEITKEEK EIAKKMIVVG LWCIQPCPSD RPSMNRVVEM MEGSLDALEI
PPKPSMHIST EVITESSSLS DGGEDV
