ID   Y539_THEKO              Reviewed;         318 AA.
AC   Q5JF28;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Putative HTH-type transcriptional regulatory protein TK0539 {ECO:0000255|HAMAP-Rule:MF_00584};
GN   OrderedLocusNames=TK0539;
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
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DR   EMBL; AP006878; BAD84728.1; -; Genomic_DNA.
DR   RefSeq; WP_011249494.1; NC_006624.1.
DR   AlphaFoldDB; Q5JF28; -.
DR   SMR; Q5JF28; -.
DR   STRING; 69014.TK0539; -.
DR   EnsemblBacteria; BAD84728; BAD84728; TK0539.
DR   GeneID; 3234201; -.
DR   KEGG; tko:TK0539; -.
DR   PATRIC; fig|69014.16.peg.527; -.
DR   eggNOG; arCOG04152; Archaea.
DR   HOGENOM; CLU_075726_0_0_2; -.
DR   InParanoid; Q5JF28; -.
DR   OMA; PGVVYFR; -.
DR   OrthoDB; 76134at2157; -.
DR   PhylomeDB; Q5JF28; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   HAMAP; MF_00584; HTH_type_cro_C1; 1.
DR   InterPro; IPR020886; Arc_TR_HTH.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..318
FT                   /note="Putative HTH-type transcriptional regulatory protein
FT                   TK0539"
FT                   /id="PRO_0000144864"
FT   DOMAIN          131..189
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
FT   DNA_BIND        142..161
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
SQ   SEQUENCE   318 AA;  35866 MW;  2DF3501F655F324B CRC64;
     MERERLIKTV EAILRGAGYR VARLDLKGSC FDLVASRLFL LLFIKATVNI DTITEEQAED
     LKRLAKFFKA SPLIVGLRSK SGELEEGVVY ERFGIYALRP ETLYDALLNN ELPAVFAERG
     GLYVRINGEL LRELREKHGY SVNELAQLLG VSRKSLLNYE RGEQAVSLDV AIQLEEIFDE
     ALAEPIDILR AKVEADLNVK PETPLEREVF ERLKKLGLGL VKVKKAPFNA ISTEDDIRLL
     TGIDERKTRS TIKRAEMVAE VGRIVNSGGV FILEKTKAEV VSEVPLIPKE SLEEVKDADE
     LIELIDKLKK EIKEKLFS