ID   Y540_AQUAE              Reviewed;         214 AA.
AC   O66819;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=UPF0056 membrane protein aq_540;
GN   OrderedLocusNames=aq_540;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0056 (MarC) family. {ECO:0000305}.
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DR   EMBL; AE000657; AAC06780.1; -; Genomic_DNA.
DR   PIR; G70348; G70348.
DR   RefSeq; NP_213379.1; NC_000918.1.
DR   RefSeq; WP_010880317.1; NC_000918.1.
DR   AlphaFoldDB; O66819; -.
DR   STRING; 224324.aq_540; -.
DR   EnsemblBacteria; AAC06780; AAC06780; aq_540.
DR   KEGG; aae:aq_540; -.
DR   eggNOG; COG2095; Bacteria.
DR   HOGENOM; CLU_079909_2_1_0; -.
DR   InParanoid; O66819; -.
DR   OMA; LFVIMDP; -.
DR   OrthoDB; 1323133at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002771; Multi_antbiot-R_MarC.
DR   PANTHER; PTHR33508; PTHR33508; 1.
DR   Pfam; PF01914; MarC; 1.
DR   TIGRFAMs; TIGR00427; TIGR00427; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..214
FT                   /note="UPF0056 membrane protein aq_540"
FT                   /id="PRO_0000156906"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   214 AA;  23572 MW;  DD1A9947A5DE931D CRC64;
     MIITWMEEFG VLFVKAFLSL LAIMNPFSSV PVVISLMNEY SKEEIRVIAL KASVYAFFIL
     TFFLISGDLL FRFMGITLPA FKVGGGILLF LIALNLVQGE VTKEKGKAHE IEAALRRDNI
     ALIPLAMPLL AGPGSITTVL VLRGYLNTLE GKVALFCAIF LSSFTAFVVY SLSTFFYRVL
     GRTGINLITR ISGILLLAIS VQFVVDGLKN LLKH