ID   Y541_THEFY              Reviewed;        1018 AA.
AC   Q47SI8;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=UPF0182 protein Tfu_0541 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=Tfu_0541;
OS   Thermobifida fusca (strain YX).
OC   Bacteria; Actinobacteria; Streptosporangiales; Nocardiopsaceae;
OC   Thermobifida.
OX   NCBI_TaxID=269800;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YX;
RX   PubMed=17209016; DOI=10.1128/jb.01899-06;
RA   Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M., DiBartolo G.,
RA   Martinez M., Lapidus A., Lucas S., Copeland A., Richardson P., Wilson D.B.,
RA   Kyrpides N.;
RT   "Genome sequence and analysis of the soil cellulolytic actinomycete
RT   Thermobifida fusca YX.";
RL   J. Bacteriol. 189:2477-2486(2007).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; CP000088; AAZ54579.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q47SI8; -.
DR   SMR; Q47SI8; -.
DR   STRING; 269800.Tfu_0541; -.
DR   EnsemblBacteria; AAZ54579; AAZ54579; Tfu_0541.
DR   KEGG; tfu:Tfu_0541; -.
DR   eggNOG; COG1615; Bacteria.
DR   HOGENOM; CLU_007733_1_0_11; -.
DR   OMA; HLRYPQD; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 2.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..1018
FT                   /note="UPF0182 protein Tfu_0541"
FT                   /id="PRO_0000291302"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   REGION          497..570
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          939..965
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        556..570
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1018 AA;  112018 MW;  5DFFECAA3267AF84 CRC64;
     MSFRSPGAPT ARMPRRSRLL APVGAAVVVI IAGIMFAANF WTEYRWFGSV GYTTVFWTEL
     RTRALLFAGG ALLMALAVGL SVYFAYRTRP AYRPFSLEQQ GLDRYRSSID PHRKVFFWGL
     VGGLALLTGA SATAEWQTFL QFANATKFGA QDAQFGLDIS FYTFTYPFLQ VIIGYLYTAV
     VIAFIAGVVV HYLYGGVRLQ AQGQRVTPAA RVHLSVLLGV FLLLRAADYW LEQYGLVFSN
     RGYTFGASYT DVNAVLYAKI ILFFIALVCA VLFFANIYFK NARVPLVSLG LMVLSAILIG
     GVYPAIVQQV TVSPNEQRLE RPYIQRNIEA TRAAYGIDGA EVIDYDAQTE LTTAELAAEA
     ETIPSVRLVD PAVVSQTFQQ LQQVRGFYQF PQVLEVDRYT TSDGETVDTI VAARELDGPP
     SQEDRWLTRH LVYTHGFGMV AAAGNQVDSE GRPVFLEYNI PPTGELSQVG EGYEPRIYFG
     REGAEYVIVN AEAEYDYPVD PDTPEVPTTE DAVVPTPSPS PEADEAPAPA DSREEGSAQE
     QQDQEGQDGG EDAQGTEEEQ SGQGSGQANN YYDGKGGVQL KSFFDKLMYA LKYQEINILL
     NNAISNESQI IYVRDPAERV EKVAPFLTVD GKAYPAVVDG RIVWIVDAYT TSDRYPYSTP
     IDLAQATTDT FTESTTAVNA LPGNRVNYIR NSVKATVDAY DGTVTLYGWD EEDPVLQTWS
     KAFPGVVTSK DEISDTLLSH LRYPDDLYKV QREILERYHI TNADAFYGGQ DFWTVPNDPK
     PQAGNNPEPP YRQTIRFPGD DTPTYSLTST FVPRGRENLA AFMAVNSDAS SEDYGQMRIL
     ELPRSTAVQG PGQIQNTFQS SAEVREVLLP LEQSSAQVTY GNLLTLPFAG GLLYVEPLYV
     QAGGSDASYP LLQQVLVGFG DQVAIGSNLQ EALNNLFDGD EAPLEEPTTD GEAREEEEQP
     QASSDLAQAL EDAAEAYEEG QAALREGDFA AYGEANERLK EALDRAKAAS GSNEEKDE