ID   Y544_THEAB              Reviewed;         223 AA.
AC   B7IG18;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=UPF0173 metal-dependent hydrolase THA_544 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=THA_544;
OS   Thermosipho africanus (strain TCF52B).
OC   Bacteria; Thermotogae; Thermotogales; Fervidobacteriaceae; Thermosipho.
OX   NCBI_TaxID=484019;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TCF52B;
RX   PubMed=19124572; DOI=10.1128/jb.01448-08;
RA   Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D.,
RA   Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F.;
RT   "The genome of Thermosipho africanus TCF52B: lateral genetic connections to
RT   the Firmicutes and Archaea.";
RL   J. Bacteriol. 191:1974-1978(2009).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; CP001185; ACJ75032.1; -; Genomic_DNA.
DR   RefSeq; WP_012579640.1; NC_011653.1.
DR   AlphaFoldDB; B7IG18; -.
DR   SMR; B7IG18; -.
DR   STRING; 484019.THA_544; -.
DR   EnsemblBacteria; ACJ75032; ACJ75032; THA_544.
DR   KEGG; taf:THA_544; -.
DR   eggNOG; COG2220; Bacteria.
DR   HOGENOM; CLU_070010_4_0_0; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 767622at2; -.
DR   Proteomes; UP000002453; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..223
FT                   /note="UPF0173 metal-dependent hydrolase THA_544"
FT                   /id="PRO_1000197818"
SQ   SEQUENCE   223 AA;  24570 MW;  ED6212CC378C05CE CRC64;
     MKITFLGHAV FLIETNKKIL IDPFITGNPA FPKDFSFDKI DYILVTHGHG DHIGDTVELS
     KKYNATVVSN FEICNYLQKK GVNKVHPMHI GGSFNFDFGK LKMTPALHGS GIIEGDNIIY
     GGNPGGFVIY SEKSVYHAGD TGLTKDMELL RGVDVAILPI GGNFVMDVED ALKAVEMIKP
     KVVIPMHYNT WDIISADEEK FKKGSKQLGV KCIILKPGES VEI