ID   Y553_TREPA              Reviewed;         403 AA.
AC   O83564;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Putative transport protein TP_0553;
GN   OrderedLocusNames=TP_0553;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC       family. {ECO:0000305}.
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DR   EMBL; AE000520; AAC26557.1; -; Genomic_DNA.
DR   PIR; E71309; E71309.
DR   RefSeq; WP_010882000.1; NC_021490.2.
DR   AlphaFoldDB; O83564; -.
DR   STRING; 243276.TPANIC_0553; -.
DR   EnsemblBacteria; AAC26557; AAC26557; TP_0553.
DR   GeneID; 57879079; -.
DR   KEGG; tpa:TP_0553; -.
DR   eggNOG; COG0628; Bacteria.
DR   HOGENOM; CLU_041771_2_3_12; -.
DR   OMA; EIAYVYQ; -.
DR   OrthoDB; 944044at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002549; AI-2E-like.
DR   PANTHER; PTHR21716; PTHR21716; 1.
DR   Pfam; PF01594; AI-2E_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..403
FT                   /note="Putative transport protein TP_0553"
FT                   /id="PRO_0000148324"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        350..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   403 AA;  45284 MW;  5A8370CD6749115B CRC64;
     MEKQSPAQTI SLFVLLALMF VLVCMLFVPY LTVLLWSSIL AILLSPCYRA LCARIDMHAF
     TRTRHLVSHM NGEDGCTAAI TRATRFQKKM LAAVFSLVIT LLVTTVFFFI AISLFGQGKL
     LFDKLSLFFR EYDLFEGAKQ RSFTALIFKL SRGTVDISTL NVEEHLLRFF GKHVESVFVY
     TQIFVKNIAR AALSTLFFSF TLYFFFLDGE HLSCLLIAAL PLRKRASAQL LEKCKEATRH
     LFKGLFSIAF YQTCVAFVFY GIFRVEGPMA LAMLTFFASF LPLVGCACVW LPVGISIGFT
     SGWMRGTLFL FVAGSSITII DSFLRPLLLQ NKMRIHPLLI FFSMLGGVQT FGFNGMVLGP
     ILVILLFTVI DLTHDGESHY TSIFHDPPAA GVHAQSIHRQ GKK