ID   Y557_STRPF              Reviewed;         296 AA.
AC   Q1J7K4;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-JUN-2006, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Nucleotide-binding protein MGAS10750_Spy0557 {ECO:0000255|HAMAP-Rule:MF_00636};
GN   OrderedLocusNames=MGAS10750_Spy0557;
OS   Streptococcus pyogenes serotype M4 (strain MGAS10750).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=370554;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGAS10750;
RX   PubMed=16636287; DOI=10.1073/pnas.0510279103;
RA   Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R.,
RA   Musser J.M.;
RT   "Molecular genetic anatomy of inter- and intraserotype variation in the
RT   human bacterial pathogen group A Streptococcus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006).
CC   -!- FUNCTION: Displays ATPase and GTPase activities. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
CC   -!- SIMILARITY: Belongs to the RapZ-like family. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
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DR   EMBL; CP000262; ABF37507.1; -; Genomic_DNA.
DR   RefSeq; WP_002985434.1; NC_008024.1.
DR   AlphaFoldDB; Q1J7K4; -.
DR   SMR; Q1J7K4; -.
DR   EnsemblBacteria; ABF37507; ABF37507; MGAS10750_Spy0557.
DR   GeneID; 57852348; -.
DR   KEGG; spi:MGAS10750_Spy0557; -.
DR   HOGENOM; CLU_059558_0_0_9; -.
DR   OMA; TVMSFGF; -.
DR   Proteomes; UP000002434; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00636; RapZ_like; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005337; RapZ-like.
DR   PANTHER; PTHR30448; PTHR30448; 1.
DR   Pfam; PF03668; ATP_bind_2; 1.
DR   PIRSF; PIRSF005052; P-loopkin; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; GTP-binding; Nucleotide-binding.
FT   CHAIN           1..296
FT                   /note="Nucleotide-binding protein MGAS10750_Spy0557"
FT                   /id="PRO_0000259012"
FT   BINDING         13..20
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
FT   BINDING         63..66
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
SQ   SEQUENCE   296 AA;  33587 MW;  30BC22DE267BA777 CRC64;
     MSDKHINLVI VTGMSGAGKT VAIQSFEDLG YFTIDNMPPA LVPKFLELIE QTNENRRVAL
     VVDMRSRLFF KEINSTLDSI ESNPSIDFRI LFLDATDGEL VSRYKETRRS HPLAADGRVL
     DGIRLERELL SPLKSMSQHV VDTTKLTPRQ LRKTISDQFS EGSNQASFRI EVMSFGFKYG
     LPLDADLVFD VRFLPNPYYQ VELREKTGLD EDVFNYVMSH PESEVFYKHL LNLIVPILPA
     YQKEGKSVLT VAIGCTGGQH RSVAFAHCLA ESLATDWSVN ESHRDQNRRK ETVNRS