Y5597_ARATH
ID Y5597_ARATH Reviewed; 829 AA.
AC Q9FN92;
DT 13-OCT-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=Probable receptor-like protein kinase At5g59700;
DE EC=2.7.11.-;
DE Flags: Precursor;
GN OrderedLocusNames=At5g59700; ORFNames=T5I8.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=19529822; DOI=10.1093/mp/ssn083;
RA Chae L., Sudat S., Dudoit S., Zhu T., Luan S.;
RT "Diverse transcriptional programs associated with environmental stress and
RT hormones in the Arabidopsis receptor-like kinase gene family.";
RL Mol. Plant 2:84-107(2009).
CC -!- INTERACTION:
CC Q9FN92; Q9SCZ4: FER; NbExp=3; IntAct=EBI-17071988, EBI-15880405;
CC Q9FN92; Q9LX66: HERK1; NbExp=4; IntAct=EBI-17071988, EBI-22028097;
CC Q9FN92; B3GS44: LRE; NbExp=2; IntAct=EBI-17071988, EBI-21914693;
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
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DR EMBL; AB006705; BAB09508.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97221.1; -; Genomic_DNA.
DR RefSeq; NP_200778.1; NM_125362.3.
DR AlphaFoldDB; Q9FN92; -.
DR SMR; Q9FN92; -.
DR BioGRID; 21335; 12.
DR IntAct; Q9FN92; 15.
DR STRING; 3702.AT5G59700.1; -.
DR iPTMnet; Q9FN92; -.
DR PaxDb; Q9FN92; -.
DR PRIDE; Q9FN92; -.
DR ProteomicsDB; 242907; -.
DR EnsemblPlants; AT5G59700.1; AT5G59700.1; AT5G59700.
DR GeneID; 836091; -.
DR Gramene; AT5G59700.1; AT5G59700.1; AT5G59700.
DR KEGG; ath:AT5G59700; -.
DR Araport; AT5G59700; -.
DR TAIR; locus:2174249; AT5G59700.
DR eggNOG; KOG1187; Eukaryota.
DR HOGENOM; CLU_000288_42_1_1; -.
DR OMA; FSHVDAT; -.
DR OrthoDB; 684563at2759; -.
DR PhylomeDB; Q9FN92; -.
DR PRO; PR:Q9FN92; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FN92; baseline and differential.
DR Genevisible; Q9FN92; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IBA:GO_Central.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:InterPro.
DR GO; GO:0046777; P:protein autophosphorylation; IBA:GO_Central.
DR InterPro; IPR045272; ANXUR1-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR024788; Malectin-like_Carb-bd_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27003; PTHR27003; 1.
DR Pfam; PF12819; Malectin_like; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Cell membrane; Glycoprotein; Kinase; Membrane;
KW Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase;
KW Signal; Transferase; Transmembrane; Transmembrane helix.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..829
FT /note="Probable receptor-like protein kinase At5g59700"
FT /id="PRO_0000386563"
FT TOPO_DOM 25..406
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 407..427
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 428..829
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 482..755
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT ACT_SITE 606
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT ECO:0000255|PROSITE-ProRule:PRU10027"
FT BINDING 488..496
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 510
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT CARBOHYD 40
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 216
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 279
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 380
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 829 AA; 91964 MW; 08523C03192FE1D9 CRC64;
MGGEKFGFLI WILSIPCLIF LCYGYVPVDN YLINCGSSTN VTVTSRVFIS DNLASNFLTS
PNEILAASNR NSNSDIYQTA RIFTGISKYR FSVARGRHWI RLHFNPFQYQ NFQMVSAKFS
VSSETHVLLS DFTVSSRVMK EYSLNVATDH LELTFTPSGD SFAFLNALEV VSVPDTLFSG
DPSFAGSPGK FQGLSWQALE TVYRVNMGGP RVTPSNDTLS RIWEPDSEFL VEKNLVKSVS
KIASVDYVPG FATEETAPRT VYGTCTEMNS ADNPSSNFNV TWDFDVDPGF QYFLRFHFCD
IVSKALNQLY FNLYVDSMDV VENLDLSSYL SNTLSGAYAM DFVTGSAKLT KRIRVSIGRS
SVHTDYPTAI LNGLEIMKMN NSKSQLSIGT FLPSGSSSTT KKNVGMIIGL TIGSLLALVV
LGGFFVLYKK RGRDQDGNSK TWIPLSSNGT TSSSNGTTLA SIASNSSYRI PLVAVKEATN
SFDENRAIGV GGFGKVYKGE LHDGTKVAVK RANPKSQQGL AEFRTEIEML SQFRHRHLVS
LIGYCDENNE MILVYEYMEN GTLKSHLYGS GLLSLSWKQR LEICIGSARG LHYLHTGDAK
PVIHRDVKSA NILLDENLMA KVADFGLSKT GPEIDQTHVS TAVKGSFGYL DPEYFRRQQL
TEKSDVYSFG VVMFEVLCAR PVIDPTLTRE MVNLAEWAMK WQKKGQLEHI IDPSLRGKIR
PDSLRKFGET GEKCLADYGV DRPSMGDVLW NLEYALQLQE AVVDGDPEDS TNMIGELPLR
FNDYNHGDTS VNFSVAKEGR FDEEESSVDD SSGVSMSKVF SQLIKSEGR
