ID   Y559_MYCTU              Reviewed;         112 AA.
AC   P9WKL3; F2GMK4; L0T718; O06425; Q7D9M9;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 30.
DE   RecName: Full=Uncharacterized protein Rv0559c;
DE   Flags: Precursor;
GN   OrderedLocusNames=Rv0559c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   INDUCTION BY SALICYLATE, AND OPERON STRUCTURE.
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=16175359; DOI=10.1007/s00203-005-0037-9;
RA   Denkin S., Byrne S., Jie C., Zhang Y.;
RT   "Gene expression profiling analysis of Mycobacterium tuberculosis genes in
RT   response to salicylate.";
RL   Arch. Microbiol. 184:152-157(2005).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
RN   [4]
RP   INDUCTION.
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=22485172; DOI=10.1371/journal.pone.0034471;
RA   Schuessler D.L., Parish T.;
RT   "The promoter of Rv0560c is induced by salicylate and structurally-related
RT   compounds in Mycobacterium tuberculosis.";
RL   PLoS ONE 7:E34471-E34471(2012).
CC   -!- INDUCTION: By salicylate. Part of the Rv0560c-Rv0559c operon. Operon
CC       induction is slow but is maintained for at least 2 weeks in aerobic
CC       culture in the presence of salicylate. {ECO:0000269|PubMed:16175359,
CC       ECO:0000269|PubMed:22485172}.
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DR   EMBL; AL123456; CCP43297.1; -; Genomic_DNA.
DR   PIR; B70549; B70549.
DR   RefSeq; NP_215073.1; NC_000962.3.
DR   RefSeq; WP_003402937.1; NZ_NVQJ01000036.1.
DR   AlphaFoldDB; P9WKL3; -.
DR   STRING; 83332.Rv0559c; -.
DR   PaxDb; P9WKL3; -.
DR   DNASU; 887569; -.
DR   GeneID; 45424523; -.
DR   GeneID; 887569; -.
DR   KEGG; mtu:Rv0559c; -.
DR   TubercuList; Rv0559c; -.
DR   eggNOG; ENOG5030R22; Bacteria.
DR   OMA; LHTYGIY; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005576; C:extracellular region; HDA:MTBBASE.
DR   GO; GO:0009274; C:peptidoglycan-based cell wall; HDA:MTBBASE.
DR   InterPro; IPR007969; DUF732.
DR   Pfam; PF05305; DUF732; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..112
FT                   /note="Uncharacterized protein Rv0559c"
FT                   /id="PRO_0000419778"
SQ   SEQUENCE   112 AA;  12117 MW;  8A3AF97188684AD4 CRC64;
     MKGTKLAVVV GMTVAAVSLA APAQADDYDA PFNNTIHRFG IYGPQDYNAW LAKISCERLS
     RGVDGDAYKS ATFLQRNLPR GTTQGQAFQF LGAAIDHYCP EHVGVLQRAG TR