Y5600_ARATH
ID Y5600_ARATH Reviewed; 499 AA.
AC Q9LVG9;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=BTB/POZ domain-containing protein At5g60050;
GN OrderedLocusNames=At5g60050; ORFNames=MGO3.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP DOMAIN BTB.
RX PubMed=15749712; DOI=10.1074/jbc.m413247200;
RA Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L.,
RA Vierstra R.D.;
RT "Cullins 3a and 3b assemble with members of the broad
RT complex/tramtrack/bric-a-brac (BTB) protein family to form essential
RT ubiquitin-protein ligases (E3s) in Arabidopsis.";
RL J. Biol. Chem. 280:18810-18821(2005).
CC -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC ubiquitination and subsequent proteasomal degradation of target
CC proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- DOMAIN: The BTB/POZ domain mediates the interaction with some component
CC of ubiquitin ligase complexes. {ECO:0000269|PubMed:15749712}.
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DR EMBL; AB019231; BAA96934.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97271.1; -; Genomic_DNA.
DR EMBL; AK117505; BAC42168.1; -; mRNA.
DR EMBL; BT006037; AAP04024.1; -; mRNA.
DR RefSeq; NP_200813.1; NM_125398.2.
DR AlphaFoldDB; Q9LVG9; -.
DR BioGRID; 21371; 1.
DR PaxDb; Q9LVG9; -.
DR PRIDE; Q9LVG9; -.
DR ProteomicsDB; 243116; -.
DR EnsemblPlants; AT5G60050.1; AT5G60050.1; AT5G60050.
DR GeneID; 836127; -.
DR Gramene; AT5G60050.1; AT5G60050.1; AT5G60050.
DR KEGG; ath:AT5G60050; -.
DR Araport; AT5G60050; -.
DR TAIR; locus:2164185; AT5G60050.
DR eggNOG; ENOG502QPNN; Eukaryota.
DR HOGENOM; CLU_025834_0_0_1; -.
DR InParanoid; Q9LVG9; -.
DR OMA; ITVCDYP; -.
DR OrthoDB; 512599at2759; -.
DR PhylomeDB; Q9LVG9; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9LVG9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LVG9; baseline and differential.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR038920; BTB/POZ_dom_prot.
DR PANTHER; PTHR31060; PTHR31060; 1.
DR PROSITE; PS50097; BTB; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..499
FT /note="BTB/POZ domain-containing protein At5g60050"
FT /id="PRO_0000408531"
FT DOMAIN 99..172
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT REGION 18..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..52
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 499 AA; 56939 MW; 65E4998C97A01CC6 CRC64;
MASREVSTMI KQGFIADPSL SFSPSRISSP IKLSTASPPL PPPPPPPPNE STLSNPTLFD
MMSDEHNREL PRRKSHARVA QILTEFKNGV VYGHSLGPGD VKLTVVGKDG YRVTMDVHRK
VLSEKSRFFM EKMNSRREKG VSHMVEISEC DDLEIYVETV VLMYSDDLKK KLIGENVIKI
LALLKVSAAI SFDEGVMSCL EHLEAVPWSE DEEETVVTCL EELHLPDDSV TLILQRVSSQ
PSTSSTRTRT DDIFSKLLTG VLQAKDDKAR REMKVLIFKL VREEADYDVS RDTLYGLCHR
CLTSLVLCLS EVTTQMNDPG KDRGALMGEI AREADNMLWM VDILIEKKLC SEFVKLWADQ
KELANLHSKI PTMYRHEISK ITAQICVGIG KGRILVNRET RFAVLNTWLE ALYDDFGWMR
RLSSRSLDRK LVEDGLSQTI LTLSLRQQQV ILMKWFDRFL SKGDDCPNVQ RAFEVWWRRA
FIRQVLTEPD EPRLQITLY
