ID   Y5602_DICDI             Reviewed;         451 AA.
AC   Q54TW5;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Putative uncharacterized transmembrane protein DDB_G0281465;
GN   ORFNames=DDB_G0281465;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AAFI02000041; EAL66714.1; -; Genomic_DNA.
DR   RefSeq; XP_640696.1; XM_635604.1.
DR   AlphaFoldDB; Q54TW5; -.
DR   SMR; Q54TW5; -.
DR   PaxDb; Q54TW5; -.
DR   EnsemblProtists; EAL66714; EAL66714; DDB_G0281465.
DR   GeneID; 8623082; -.
DR   KEGG; ddi:DDB_G0281465; -.
DR   dictyBase; DDB_G0281465; -.
DR   eggNOG; ENOG502RCJR; Eukaryota.
DR   HOGENOM; CLU_607535_0_0_1; -.
DR   InParanoid; Q54TW5; -.
DR   OMA; NPSKREC; -.
DR   PRO; PR:Q54TW5; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..451
FT                   /note="Putative uncharacterized transmembrane protein
FT                   DDB_G0281465"
FT                   /id="PRO_0000352434"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        392..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          250..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   451 AA;  51106 MW;  7159756B165C2701 CRC64;
     MEISPTKIKS VLLKLIQILF FTISISIYID LVGNSNNKNN INNNINNEEL LLNKQIQIYY
     WFVGIILFSI AWSIGTFKWL SRFFLTFFII KSIQQLIQHL PIEFYDKLRN LIVFGTFSKF
     DFTSTGIITE SLPTLYDNFF GGNISPFSIE IIGIQSCLII FFSTLGFNIY LADKFWLIKT
     IIVDWIISAI LLIIFSITDL LMNQSNVYSV ISYIFGSNVL GFGTIKIQEF LWNLSSKYDD
     KLNSTIIKST KSNNNNNNNN NNKQDDNIIY DTDSSFNGQS SSSSSSSSSS SSSSSSATTT
     TTTLVNDNSI ISEYVTEKIM IEENGEIKEQ EVQVDKLDYS KLNEDQLNAI LSEPILETQI
     TTRNVSYHKS TRFINNLIAP ENINSRISAK EFVGVIILWV YTISNFIISD YSLLTIPNIL
     VVVGFSGTIL TYLSTISAKR LTNKNPSKRE C