Y5613_ARATH
ID Y5613_ARATH Reviewed; 842 AA.
AC Q9FLJ8;
DT 13-OCT-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Probable receptor-like protein kinase At5g61350;
DE EC=2.7.11.-;
DE Flags: Precursor;
GN OrderedLocusNames=At5g61350; ORFNames=MFB13.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=19529822; DOI=10.1093/mp/ssn083;
RA Chae L., Sudat S., Dudoit S., Zhu T., Luan S.;
RT "Diverse transcriptional programs associated with environmental stress and
RT hormones in the Arabidopsis receptor-like kinase gene family.";
RL Mol. Plant 2:84-107(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
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DR EMBL; AB010073; BAB08490.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97457.1; -; Genomic_DNA.
DR RefSeq; NP_200943.1; NM_125528.2.
DR AlphaFoldDB; Q9FLJ8; -.
DR SMR; Q9FLJ8; -.
DR STRING; 3702.AT5G61350.1; -.
DR iPTMnet; Q9FLJ8; -.
DR PaxDb; Q9FLJ8; -.
DR PRIDE; Q9FLJ8; -.
DR ProteomicsDB; 242834; -.
DR EnsemblPlants; AT5G61350.1; AT5G61350.1; AT5G61350.
DR GeneID; 836256; -.
DR Gramene; AT5G61350.1; AT5G61350.1; AT5G61350.
DR KEGG; ath:AT5G61350; -.
DR Araport; AT5G61350; -.
DR TAIR; locus:2163158; AT5G61350.
DR eggNOG; KOG1187; Eukaryota.
DR HOGENOM; CLU_000288_42_1_1; -.
DR InParanoid; Q9FLJ8; -.
DR OMA; IAPANIY; -.
DR OrthoDB; 684563at2759; -.
DR PhylomeDB; Q9FLJ8; -.
DR PRO; PR:Q9FLJ8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FLJ8; baseline and differential.
DR Genevisible; Q9FLJ8; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IDA:TAIR.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:InterPro.
DR GO; GO:0097275; P:cellular ammonium homeostasis; IMP:TAIR.
DR GO; GO:0046777; P:protein autophosphorylation; IBA:GO_Central.
DR GO; GO:0051924; P:regulation of calcium ion transport; IMP:TAIR.
DR GO; GO:0080147; P:root hair cell development; IMP:TAIR.
DR InterPro; IPR045272; ANXUR1-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR024788; Malectin-like_Carb-bd_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27003; PTHR27003; 1.
DR Pfam; PF12819; Malectin_like; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Glycoprotein; Kinase; Membrane; Nucleotide-binding;
KW Reference proteome; Serine/threonine-protein kinase; Signal; Transferase;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..842
FT /note="Probable receptor-like protein kinase At5g61350"
FT /id="PRO_0000386564"
FT TOPO_DOM 28..425
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 426..446
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 447..842
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 525..803
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT ACT_SITE 655
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT ECO:0000255|PROSITE-ProRule:PRU10027"
FT BINDING 531..539
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 553
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT CARBOHYD 81
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 125
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 252
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 294
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 359
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 365
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 842 AA; 92687 MW; 5605D0270614FBF6 CRC64;
MGGDFRHFSS HVSLLLLFLL IVKSSSSFTP ADNYLIDCGS SDETKLSDGR NFKSDQQSVA
FLQTDEDIKT SVDSIPITDS NASTLPLYLT ARIFAGKSTY SFYISRPGRH WIRLHFYPLN
HPLYNLTNSV FSVTTDTTVL LHDFSAGDTS SIVFKEYLIY AAEKLSLYFK PHKGSTAFIN
AVEIVSVPDE LVPDSASSVP QAPDFKGLSS FSLEILHRIN IGGDLISPKI DPLSRTWLSD
KPYNTFPEGS RNVTVDPSTI TYPDGGATAL IAPNPVYATA EEMADAQTSQ PNFNLSWRMS
VDFGHDYFIR LHFCDIVSKS LNDLIFNVFI NKLSAISALD LSSLTSALGT AYYADFVLNA
STITNGSILV QVGPTPNLQS GKPNAILNGL EIMKLNNAAG SLDGLFGVDG KYKGPIGGMS
SKKLAIAGIG FVMALTAFLG VVVLLVRWQR RPKDWQKQNS FSSWLLPLHA SHSSYISSKG
GSTSRRMSIF GSKKSKSNGF SSFFSNQGLG RYFPFTELQT ATQNFDENAV CGVGGFGKVY
IGEIDGGTQV AIKRGSQSSE QGINEFQTEI QMLSKLRHRH LVSLIGFCDE NKEMILVYEY
MSNGPLRDHL YGSKENDPNP IPTLSWKQRL EICIGSARGL HYLHTGAAQG IIHRDVKTTN
ILLDENLVAK VSDFGLSKDA PMDEGHVSTA VKGSFGYLDP EYFRRQQLTD KSDVYSFGVV
LFEVLCARPV INPQLPREQV NLAEYAMNLH RKGMLEKIID PKIVGTISKG SLRKFVEAAE
KCLAEYGVDR PGMGDVLWNL EYALQLQEAS AQVDLSEDKT TMNIEMDLIP GEEMQSPSHS
IP
