ID   CASB_CAMDR              Reviewed;         232 AA.
AC   Q9TVD0;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Beta-casein;
DE   Flags: Precursor;
GN   Name=CSN2;
OS   Camelus dromedarius (Dromedary) (Arabian camel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX   NCBI_TaxID=9838;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE, PHOSPHORYLATION AT
RP   SER-30; SER-32; SER-33 AND SER-34, AND MASS SPECTROMETRY.
RC   STRAIN=Somali; TISSUE=Mammary gland;
RX   PubMed=9627840; DOI=10.1017/s0022029997002847;
RA   Kappeler S., Farah Z., Puhan Z.;
RT   "Sequence analysis of Camelus dromedarius milk caseins.";
RL   J. Dairy Res. 65:209-222(1998).
CC   -!- FUNCTION: Important role in determination of the surface properties of
CC       the casein micelles. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Mammary gland specific. Secreted in milk.
CC   -!- MASS SPECTROMETRY: Mass=24900; Method=MALDI; Note=with 3 phosphate
CC       groups.; Evidence={ECO:0000269|PubMed:9627840};
CC   -!- SIMILARITY: Belongs to the beta-casein family. {ECO:0000305}.
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DR   EMBL; AJ012630; CAA10079.1; -; mRNA.
DR   PIR; A60305; A60305.
DR   RefSeq; NP_001290492.1; NM_001303563.1.
DR   AlphaFoldDB; Q9TVD0; -.
DR   STRING; 9838.ENSCDRP00005010646; -.
DR   iPTMnet; Q9TVD0; -.
DR   PRIDE; Q9TVD0; -.
DR   GeneID; 105090953; -.
DR   KEGG; cdk:105090953; -.
DR   CTD; 1447; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR001588; Casein.
DR   InterPro; IPR016345; Casein_beta.
DR   PANTHER; PTHR11500; PTHR11500; 1.
DR   Pfam; PF00363; Casein; 1.
DR   PIRSF; PIRSF002372; Beta-casein; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Milk protein; Phosphoprotein; Secreted; Signal.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000250"
FT   CHAIN           16..232
FT                   /note="Beta-casein"
FT                   /id="PRO_0000004472"
FT   MOD_RES         30
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000305|PubMed:9627840"
FT   MOD_RES         32
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000305|PubMed:9627840"
FT   MOD_RES         33
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000305|PubMed:9627840"
FT   MOD_RES         34
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000305|PubMed:9627840"
SQ   SEQUENCE   232 AA;  26218 MW;  A0F9F41D2EA7C518 CRC64;
     MKVLILACRV ALALAREKEE FKTAGEALES ISSSEESITH INKQKIEKFK IEEQQQTEDE
     QQDKIYTFPQ PQSLVYSHTE PIPYPILPQN FLPPLQPAVM VPFLQPKVMD VPKTKETIIP
     KRKEMPLLQS PVVPFTESQS LTLTDLENLH LPLPLLQSLM YQIPQPVPQT PMIPPQSLLS
     LSQFKVLPVP QQMVPYPQRA MPVQAVLPFQ EPVPDPVRGL HPVPQPLVPV IA