ID   Y563_MYCLB              Reviewed;         298 AA.
AC   B8ZUN6;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Nucleotide-binding protein MLBr00563 {ECO:0000255|HAMAP-Rule:MF_00636};
GN   OrderedLocusNames=MLBr00563;
OS   Mycobacterium leprae (strain Br4923).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=561304;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Br4923;
RX   PubMed=19881526; DOI=10.1038/ng.477;
RA   Monot M., Honore N., Garnier T., Zidane N., Sherafi D., Paniz-Mondolfi A.,
RA   Matsuoka M., Taylor G.M., Donoghue H.D., Bouwman A., Mays S., Watson C.,
RA   Lockwood D., Khamispour A., Dowlati Y., Jianping S., Rea T.H.,
RA   Vera-Cabrera L., Stefani M.M., Banu S., Macdonald M., Sapkota B.R.,
RA   Spencer J.S., Thomas J., Harshman K., Singh P., Busso P., Gattiker A.,
RA   Rougemont J., Brennan P.J., Cole S.T.;
RT   "Comparative genomic and phylogeographic analysis of Mycobacterium
RT   leprae.";
RL   Nat. Genet. 41:1282-1289(2009).
CC   -!- FUNCTION: Displays ATPase and GTPase activities. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
CC   -!- SIMILARITY: Belongs to the RapZ-like family. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FM211192; CAR70656.1; -; Genomic_DNA.
DR   RefSeq; WP_010907801.1; NC_011896.1.
DR   AlphaFoldDB; B8ZUN6; -.
DR   SMR; B8ZUN6; -.
DR   EnsemblBacteria; CAR70656; CAR70656; MLBr00563.
DR   KEGG; mlb:MLBr00563; -.
DR   HOGENOM; CLU_059558_0_0_11; -.
DR   OMA; TVMSFGF; -.
DR   OrthoDB; 1603998at2; -.
DR   Proteomes; UP000006900; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00636; RapZ_like; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005337; RapZ-like.
DR   PANTHER; PTHR30448; PTHR30448; 1.
DR   Pfam; PF03668; ATP_bind_2; 1.
DR   PIRSF; PIRSF005052; P-loopkin; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; GTP-binding; Nucleotide-binding.
FT   CHAIN           1..298
FT                   /note="Nucleotide-binding protein MLBr00563"
FT                   /id="PRO_1000147365"
FT   BINDING         21..28
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
FT   BINDING         72..75
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
SQ   SEQUENCE   298 AA;  32607 MW;  4E4E364E92F20D96 CRC64;
     MSGNNHPGDA SAEIDVVLVT GLSGAGRGTA AKVLEDLGWY VADNLPPQLI TWMVDFGLAA
     GSRITQLAVV MDVRSRGFTG DLDSVRRELA TRNIIPRVVF MEASDDMLVR RYEQNRRSHP
     LQGEQTLAEG IAAERRMLAP VRATADLIID TSALSVPGLR ESIERAFGGD ASATTSVTVE
     SFGFKYGLPM DADIVMDVRF LPNPHWVDEL RSLTGQHSAV RDYVLGQPGA AEFLRTYRRL
     LSLVVDGYRR EGKRYMTVAI GCTGGKHRSV AIAEALMGLL QSDLQLSVRV LHRDLGRE