ID   Y564_TREPA              Reviewed;         678 AA.
AC   O83575;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Uncharacterized protein TP_0564;
GN   OrderedLocusNames=TP_0564;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65547.1; -; Genomic_DNA.
DR   PIR; B71308; B71308.
DR   RefSeq; WP_010882011.1; NC_021490.2.
DR   AlphaFoldDB; O83575; -.
DR   IntAct; O83575; 4.
DR   STRING; 243276.TPANIC_0564; -.
DR   PRIDE; O83575; -.
DR   EnsemblBacteria; AAC65547; AAC65547; TP_0564.
DR   KEGG; tpa:TP_0564; -.
DR   eggNOG; ENOG502ZX8M; Bacteria.
DR   HOGENOM; CLU_422063_0_0_12; -.
DR   OMA; WENHYLA; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..678
FT                   /note="Uncharacterized protein TP_0564"
FT                   /id="PRO_0000202274"
FT   TRANSMEM        228..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        263..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        300..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        334..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        361..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        387..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        420..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        455..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          653..678
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   678 AA;  76524 MW;  FBCEE74A937804EB CRC64;
     MTRVCRALLF VLCGIFVHAQ ENELHFFGPR TDVLVVFTAS REAQERETRA VQQLRLLVQD
     FEHQTPDVSV LVAITAHDHP PVPDFVPVDR LTGTKKLISL ISSYKAPIVL ILDETTGPPR
     LHTGAHRTVC PPWLLQAVYQ HLTSHHVPIR YRDFDAILHR LGWLHEDPRH ALYIKEHIPA
     VRMENSLYPP GALHTLPALL TQVYSEEWDT HYVSVSYGGT LYLIREQFFV ILILGAVITL
     LLSLAIFSFL SDSRKRHYWN TILAMWWLPA ILGVLSVCSV FVATQLTALF FLIRFGTHTS
     TGALPLLALI VKHSIAIALS CVCMANSKTI RDSMLHNGFI GGYLASTLCL LYAVLFSVID
     FSLSAVFALE YALSLVFFSA QRKTTRRIML AMMFLLFAPF LYAYLKNSAV TAPLSFHQSN
     VFFALGCVPF MLFMLTLFFE REKSHPRIPF IRRRNLLLSG ALLTVLVING VLWSVSLSST
     RIPQEITACY RISERGLTLS LHSPLPIPRH IRARTHARLS TAEIQKAQDH LQISMDSRSY
     FGGRINVLEV RSQLRAQAIE LRITSPHGTA AYEADRPFTR LEQGSVVRFI SQARPPLPFT
     VTFSGDQNST MQVQATVWTY DNPLQDAPPV MQDTTVRFIP MFELTRDVLF PSPSSQGVHA
     TPEKNACIRD ETVPNLQE