ID   Y570_CORDI              Reviewed;         561 AA.
AC   Q6NJ43;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Uncharacterized transporter DIP0570;
GN   OrderedLocusNames=DIP0570;
OS   Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype
OS   gravis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=257309;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700971 / NCTC 13129 / Biotype gravis;
RX   PubMed=14602910; DOI=10.1093/nar/gkg874;
RA   Cerdeno-Tarraga A.-M., Efstratiou A., Dover L.G., Holden M.T.G.,
RA   Pallen M.J., Bentley S.D., Besra G.S., Churcher C.M., James K.D.,
RA   De Zoysa A., Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N.,
RA   Holroyd S., Jagels K., Moule S., Quail M.A., Rabbinowitsch E.,
RA   Rutherford K.M., Thomson N.R., Unwin L., Whitehead S., Barrell B.G.,
RA   Parkhill J.;
RT   "The complete genome sequence and analysis of Corynebacterium diphtheriae
RT   NCTC13129.";
RL   Nucleic Acids Res. 31:6516-6523(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; BX248355; CAE49082.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6NJ43; -.
DR   STRING; 257309.DIP0570; -.
DR   EnsemblBacteria; CAE49082; CAE49082; DIP0570.
DR   KEGG; cdi:DIP0570; -.
DR   HOGENOM; CLU_035023_3_0_11; -.
DR   OMA; AMWLIRL; -.
DR   Proteomes; UP000002198; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 1.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR018225; Transaldolase_AS.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; SSF116726; 1.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 2.
DR   PROSITE; PS51202; RCK_C; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..561
FT                   /note="Uncharacterized transporter DIP0570"
FT                   /id="PRO_0000208765"
FT   TRANSMEM        27..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        115..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        383..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        409..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        441..463
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        478..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          292..373
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ   SEQUENCE   561 AA;  59293 MW;  46E31A4E44C8B759 CRC64;
     MQIRVPQRNR GRTFPHRSSH RRTPIHILEF LAAQPLLTLA LILAVGLLIG KIRFFGISLG
     AAAVLFVALA LSTVDPALQL PPLVYQLGLA MFVYAIGLSA GSEFFAEFRH RGWKLTLFMI
     GLLMLMMAVA YGIIKLFGLD EIIGAGMFAG ALSSTPGMAA MVEMLEGIDD SVASEPVVGY
     SLAYPGAVIG SILVAAIGAK LMKVNHAADA AEEGLVSDPL EWTGVRIGPG INGTIAQLPT
     LAGEEIIATR VVHSKTFHSL AAPNDRLHEG MVLVIHGTPD ALERAIAKVG KQQDVPIEDT
     DLVYSRFTVS SKAVVGRKIS DLDTVRSGFI ISRLRRGDAD VVPEPDDVLH YSDRVRVIAP
     ANRMSEVRRF LGDSERSLAD VDLMPFAFGL VIGLAIGVIP IPLPGGNTLS LGFGGGPIVA
     GLILGALNRT GPIHWQMPYH ASRTISTFGL AIFLAGVGTS AGVGFRQALT DPASLTVIAG
     GFIVTISSAL VCALVCMPLF KLKWDEAMGV AAGCTTNPAI ISYLNGQTGT ELATRGYATV
     YPTAMIGKII ASQMLLLALI A