ID   CASB_TRIVU              Reviewed;         285 AA.
AC   Q9XSE4;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Beta-casein;
DE   Flags: Precursor;
GN   Name=CSN2; Synonyms=BCAS;
OS   Trichosurus vulpecula (Brush-tailed possum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Diprotodontia; Phalangeridae; Trichosurus.
OX   NCBI_TaxID=9337;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=10082990; DOI=10.1016/s0304-4165(99)00008-2;
RA   Ginger M.R., Piotte C.P., Otter D.E., Grigor M.R.;
RT   "Identification, characterisation and cDNA cloning of two caseins from the
RT   common brushtail possum (Trichosurus vulpecula).";
RL   Biochim. Biophys. Acta 1427:92-104(1999).
CC   -!- FUNCTION: Important role in determination of the surface properties of
CC       the casein micelles. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Mammary gland specific. Secreted in milk.
CC   -!- PTM: Phosphorylated.
CC   -!- SIMILARITY: Belongs to the beta-casein family. {ECO:0000305}.
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DR   EMBL; AF128398; AAD27846.1; -; mRNA.
DR   AlphaFoldDB; Q9XSE4; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR016345; Casein_beta.
DR   PANTHER; PTHR11500; PTHR11500; 1.
PE   2: Evidence at transcript level;
KW   Milk protein; Phosphoprotein; Secreted; Signal.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000250"
FT   CHAIN           16..285
FT                   /note="Beta-casein"
FT                   /id="PRO_0000004482"
FT   MOD_RES         23
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P05814"
FT   MOD_RES         25
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P05814"
SQ   SEQUENCE   285 AA;  33802 MW;  F937689D01167783 CRC64;
     MKLLILTCLV VLAVARPMVE KISESEEHVT DVPENEHRLE INRYLRPEYE MMNLYYQPFY
     WSEEMRNLKM TSLPKDRRMA VLKSVVSDDM LPPLQHKSLS LPKPKVLPLS HRQILPPHTL
     RMVPLSHKLF TIPKREMLPI SERERLPAHE RENLLAHERE ILLAPQREMS LIPEREILLA
     AERVVLPEQE REIRPDNERE VLAVHKREIL PASEKEKVLP LFQERVLPLH RREIVPPYQR
     DTIARREILP VDQRELMPEV VAVDLYPFFQ PVANFYYPAE LNEKN