Y5729_DICDI
ID Y5729_DICDI Reviewed; 1346 AA.
AC P0CD63;
DT 09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT 09-FEB-2010, sequence version 1.
DT 25-MAY-2022, entry version 38.
DE RecName: Full=J domain-containing protein DDB_G0295729;
GN ORFNames=DDB_G0295729;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000025; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAFI02000026; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; P0CD63; -.
DR SMR; P0CD63; -.
DR dictyBase; DDB_G0295729; -.
DR InParanoid; P0CD63; -.
DR OMA; HNGETES; -.
DR PRO; PR:P0CD63; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0030544; F:Hsp70 protein binding; IBA:GO_Central.
DR GO; GO:0071218; P:cellular response to misfolded protein; IBA:GO_Central.
DR GO; GO:0051085; P:chaperone cofactor-dependent protein refolding; IBA:GO_Central.
DR GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IBA:GO_Central.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 1.10.287.110; -; 1.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF00226; DnaJ; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; SSF46565; 1.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 4: Predicted;
KW Coiled coil; Reference proteome.
FT CHAIN 1..1346
FT /note="J domain-containing protein DDB_G0295729"
FT /id="PRO_0000391336"
FT DOMAIN 114..178
FT /note="J"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
FT REGION 57..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 214..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 746..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1026..1090
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1173..1301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1319..1346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 214..275
FT /evidence="ECO:0000255"
FT COILED 577..742
FT /evidence="ECO:0000255"
FT COILED 999..1034
FT /evidence="ECO:0000255"
FT COILED 1131..1194
FT /evidence="ECO:0000255"
FT COMPBIAS 214..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..492
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 810..826
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..880
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 895..949
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1173..1188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1189..1281
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1320..1334
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1346 AA; 155938 MW; 8F1BD2F7E0DFEFE1 CRC64;
MECNREDAIK AKELGESYFK QQNYTKSLSL FTKSKRLYPT DGIDQLISKA EAFLNNSNSN
SNNNNSSNNN NNGNSGNKSY TPSSTTTTAT TATSTLEYTK EQFEISKRVL DSKTHYEKLS
LLVNCTDVDI KRQYRALAKL LHPDKNKAPH AQQAFQEIKV ANDILSDAIQ RKRYDVQHRI
HQKPQTNRYQ QQHQQQQQQP FYNNFTYTAE TAYAQAHSHQ RQQQQQQQQQ QQYQEEFKRR
QAAVRAAQQQ QYQQQQQQQQ QQQQQQQQQQ QKRSTFVEVK CINSPNCPPI VVSQVVYDCY
NRGDVSILCN SCSKESTYVK CKSCQSIYHL DDKFKSVSHD LTCQMPSCKR SVSVGFPNLI
YDVKLKNTFM RGSKAPETTP PVTGRIPRPK FPPATTRQKQ STQPQQPIFN QPQQQPIHTQ
QQSQQQQQQQ QQQQQQQQQQ QSQQQTDFSP QKSQSQTSQK SQTSQTSQTS QKSQKSQKSQ
KSQKSPLKFG TQSEILISDD EDEIESSKTP LQTQAQQPYV VISPDQTPYT QSKTQTQTQP
TPNHTPSSQS TNYTSPNQTP LTPSQYSSSS DIAHDIDIAM ANAEKEALKR VSDEALAREA
ERNPVNHQKI IEAMRREQEK LKEEIERLKE FTRQRDFERQ LEFERQKEIE HQKEIERQKE
IERLKEENRL KEIEHQREIH RQKELEIQRE IELQKEIERI NQEEKKRKQY EQELLSKQIE
LEKEKERQLE KEIELGRERL IRGEKNFQKQ FEQQDKLQNQ SQKNNSSSFK NSLKQQQKQQ
SNPTISDDEI EPDIYPPLPK LAAFSKPVDL SEVQTKNPQS SITSFMVKKS DEKKDSPTPG
SKFSSSSSSF SSSSSSSSSS SSILQPSLPT KPTIIRNNNS PSKHQHKEIK KDNIKPNINN
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NSNSNNNQLN VETNLSFDFE
EEEFEFYTKP SNKKVENQFS DDTIFESSVF VETIDTSIKT KQQHQQQQQQ QQQQQQQQQQ
QQQQQQKLQS QQTKGTKSST PEIEKEYSSS PPHPNISSSE DEEYDGSWYS QSSTQSKELP
QTTSSTNTIP EYIPTTVKMD DIVGNDFDNV ANDYSCGYDD DDYFNDYSSH FIQQQNQINL
MEMEKEKQKE KEKRNGFERE IEKERSAQIE IELEKEKEKE KQRQKGKENN ILKSNNGNVN
NGNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNKNNDKN NYNQIRTTTP IKTSANPLKN
RNGHSNGNGN NNNNNNNNMN HDHIHSFDES EGERDEGSED ESLGILQSIN IQKVSKKRVL
SVSGKSERKS KKSHTVYHQN NKISDY
