ID   Y576_METJA              Reviewed;         347 AA.
AC   Q57996;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Uncharacterized transporter MJ0576;
GN   OrderedLocusNames=MJ0576;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the tellurite-resistance/dicarboxylate
CC       transporter (TDT) family. {ECO:0000305}.
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DR   EMBL; L77117; AAB98567.1; -; Genomic_DNA.
DR   PIR; H64371; H64371.
DR   RefSeq; WP_010870080.1; NC_000909.1.
DR   AlphaFoldDB; Q57996; -.
DR   SMR; Q57996; -.
DR   STRING; 243232.MJ_0576; -.
DR   EnsemblBacteria; AAB98567; AAB98567; MJ_0576.
DR   GeneID; 1451441; -.
DR   KEGG; mja:MJ_0576; -.
DR   eggNOG; arCOG04355; Archaea.
DR   HOGENOM; CLU_030057_6_4_2; -.
DR   InParanoid; Q57996; -.
DR   OMA; PVQSMFI; -.
DR   OrthoDB; 47545at2157; -.
DR   PhylomeDB; Q57996; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0000319; F:sulfite transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0000316; P:sulfite transport; IBA:GO_Central.
DR   Gene3D; 1.50.10.150; -; 1.
DR   InterPro; IPR004695; SLAC1/Mae1/Ssu1/TehA.
DR   InterPro; IPR011552; TehA/Mae1.
DR   InterPro; IPR038665; Voltage-dep_anion_channel_sf.
DR   Pfam; PF03595; SLAC1; 1.
DR   TIGRFAMs; TIGR00816; tdt; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..347
FT                   /note="Uncharacterized transporter MJ0576"
FT                   /id="PRO_0000106939"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        312..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   347 AA;  39557 MW;  632F7671A31DE183 CRC64;
     MLEACESKLD IIKNFVPSWF AAVMGTGILA VDSLLYSSYL PILKDVAVGL FYFNVLLFFI
     FLVPWVLRWI MFKDNALADL KHPVLSAFYP TIAVSCLVLG ADFINIGHNM FWGGVFWTLG
     AIGMFLFSLI VPFYMFKSES IKLDHVNPGW YIPPVGLIVI PIAGSLIMPH LTGVWHELTV
     LINYFGWGAG FFLYLALLAV VIYRFILHHP LPSAMAPTVW INLGPIGAGI VALINMVNNS
     PFITIKEPFY IFSFIFWGFG LWWSLMAIIM TLYYVKKLKL PYAMSWWAFI FPLGAYVASS
     HLVYKIFKFS IIDYIGFGLY WLLFFFWAIT LIKTTNKVYT GEVFKGH