ID   Y577_METJA              Reviewed;         162 AA.
AC   Q57997;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Universal stress protein MJ0577;
DE            Short=USP MJ0577;
GN   OrderedLocusNames=MJ0577;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) IN COMPLEX WITH ATP.
RX   PubMed=9860944; DOI=10.1073/pnas.95.26.15189;
RA   Zarembinski T.I., Hung L.-W., Mueller-Dieckmann H.-J., Kim K.-K.,
RA   Yokota H., Kim R., Kim S.-H.;
RT   "Structure-based assignment of the biochemical function of a hypothetical
RT   protein: a test case of structural genomics.";
RL   Proc. Natl. Acad. Sci. U.S.A. 95:15189-15193(1998).
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC       Note=Binds 1 Mn(2+) ion per subunit.;
CC   -!- SUBUNIT: Homodimer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000305}.
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DR   EMBL; L77117; AAB98568.1; -; Genomic_DNA.
DR   PIR; A64372; A64372.
DR   PDB; 1MJH; X-ray; 1.70 A; A/B=1-162.
DR   PDBsum; 1MJH; -.
DR   AlphaFoldDB; Q57997; -.
DR   SMR; Q57997; -.
DR   STRING; 243232.MJ_0577; -.
DR   EnsemblBacteria; AAB98568; AAB98568; MJ_0577.
DR   KEGG; mja:MJ_0577; -.
DR   eggNOG; arCOG00449; Archaea.
DR   HOGENOM; CLU_049301_11_2_2; -.
DR   InParanoid; Q57997; -.
DR   OMA; ILCPTDY; -.
DR   PhylomeDB; Q57997; -.
DR   EvolutionaryTrace; Q57997; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006015; Universal_stress_UspA.
DR   InterPro; IPR006016; UspA.
DR   Pfam; PF00582; Usp; 1.
DR   PRINTS; PR01438; UNVRSLSTRESS.
PE   1: Evidence at protein level;
KW   3D-structure; ATP-binding; Cytoplasm; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..162
FT                   /note="Universal stress protein MJ0577"
FT                   /id="PRO_0000147446"
FT   BINDING         11
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000269|PubMed:9860944,
FT                   ECO:0007744|PDB:1MJH"
FT   BINDING         41
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000269|PubMed:9860944,
FT                   ECO:0007744|PDB:1MJH"
FT   BINDING         127..133
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000269|PubMed:9860944,
FT                   ECO:0007744|PDB:1MJH"
FT   BINDING         141..143
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000269|PubMed:9860944,
FT                   ECO:0007744|PDB:1MJH"
FT   STRAND          7..11
FT                   /evidence="ECO:0007829|PDB:1MJH"
FT   HELIX           16..27
FT                   /evidence="ECO:0007829|PDB:1MJH"
FT   STRAND          35..43
FT                   /evidence="ECO:0007829|PDB:1MJH"
FT   HELIX           44..46
FT                   /evidence="ECO:0007829|PDB:1MJH"
FT   HELIX           67..94
FT                   /evidence="ECO:0007829|PDB:1MJH"
FT   STRAND          98..106
FT                   /evidence="ECO:0007829|PDB:1MJH"
FT   HELIX           108..118
FT                   /evidence="ECO:0007829|PDB:1MJH"
FT   STRAND          122..128
FT                   /evidence="ECO:0007829|PDB:1MJH"
FT   HELIX           141..149
FT                   /evidence="ECO:0007829|PDB:1MJH"
FT   STRAND          154..157
FT                   /evidence="ECO:0007829|PDB:1MJH"
SQ   SEQUENCE   162 AA;  18339 MW;  0A1060E6A2E6E1F4 CRC64;
     MSVMYKKILY PTDFSETAEI ALKHVKAFKT LKAEEVILLH VIDEREIKKR DIFSLLLGVA
     GLNKSVEEFE NELKNKLTEE AKNKMENIKK ELEDVGFKVK DIIVVGIPHE EIVKIAEDEG
     VDIIIMGSHG KTNLKEILLG SVTENVIKKS NKPVLVVKRK NS