Y5830_ARATH
ID Y5830_ARATH Reviewed; 654 AA.
AC Q9LVM0;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 150.
DE RecName: Full=Probable inactive receptor kinase At5g58300;
DE Flags: Precursor;
GN OrderedLocusNames=At5g58300; ORFNames=MCK7.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- INTERACTION:
CC Q9LVM0; F4I065: At1g49100; NbExp=2; IntAct=EBI-4475781, EBI-20654598;
CC Q9LVM0; Q9ZWC8: BRL1; NbExp=2; IntAct=EBI-4475781, EBI-590903;
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC inactive.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. {ECO:0000305}.
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DR EMBL; AB019228; BAA96921.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97030.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97031.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70827.1; -; Genomic_DNA.
DR EMBL; AY065009; AAL57654.1; -; mRNA.
DR EMBL; BT001138; AAN64529.1; -; mRNA.
DR RefSeq; NP_001119458.1; NM_001125986.1.
DR RefSeq; NP_001318827.1; NM_001345296.1.
DR RefSeq; NP_200638.1; NM_125215.5.
DR AlphaFoldDB; Q9LVM0; -.
DR SMR; Q9LVM0; -.
DR BioGRID; 21186; 11.
DR IntAct; Q9LVM0; 12.
DR STRING; 3702.AT5G58300.1; -.
DR iPTMnet; Q9LVM0; -.
DR SwissPalm; Q9LVM0; -.
DR PaxDb; Q9LVM0; -.
DR PRIDE; Q9LVM0; -.
DR ProteomicsDB; 243171; -.
DR EnsemblPlants; AT5G58300.1; AT5G58300.1; AT5G58300.
DR EnsemblPlants; AT5G58300.2; AT5G58300.2; AT5G58300.
DR EnsemblPlants; AT5G58300.3; AT5G58300.3; AT5G58300.
DR GeneID; 835942; -.
DR Gramene; AT5G58300.1; AT5G58300.1; AT5G58300.
DR Gramene; AT5G58300.2; AT5G58300.2; AT5G58300.
DR Gramene; AT5G58300.3; AT5G58300.3; AT5G58300.
DR KEGG; ath:AT5G58300; -.
DR Araport; AT5G58300; -.
DR TAIR; locus:2161308; AT5G58300.
DR eggNOG; ENOG502QT13; Eukaryota.
DR HOGENOM; CLU_000288_92_6_1; -.
DR InParanoid; Q9LVM0; -.
DR OMA; LAPIMNF; -.
DR OrthoDB; 389502at2759; -.
DR PhylomeDB; Q9LVM0; -.
DR PRO; PR:Q9LVM0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LVM0; baseline and differential.
DR Genevisible; Q9LVM0; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Leucine-rich repeat; Membrane; Nucleotide-binding;
KW Phosphoprotein; Receptor; Reference proteome; Repeat; Signal;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..38
FT /evidence="ECO:0000255"
FT CHAIN 39..654
FT /note="Probable inactive receptor kinase At5g58300"
FT /id="PRO_0000324847"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 113..135
FT /note="LRR 1"
FT REPEAT 137..158
FT /note="LRR 2"
FT REPEAT 159..182
FT /note="LRR 3"
FT REPEAT 183..204
FT /note="LRR 4"
FT REPEAT 205..228
FT /note="LRR 5"
FT DOMAIN 358..631
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT REGION 250..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..268
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..645
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 364..372
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 386
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT MOD_RES 360
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q94F62"
FT MOD_RES 381
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q94F62"
FT MOD_RES 441
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9LSI9"
FT MOD_RES 530
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q94AG2"
SQ SEQUENCE 654 AA; 71899 MW; 3B0B199B9213F0F5 CRC64;
MMQFHFQFYV GPVFTLRPSK GFLSTCLVSF LFVTTTFCSY AIADLNSDRQ ALLAFAASVP
HLRRLNWNST NHICKSWVGV TCTSDGTSVH ALRLPGIGLL GPIPPNTLGK LESLRILSLR
SNLLSGNLPP DIHSLPSLDY IYLQHNNFSG EVPSFVSRQL NILDLSFNSF TGKIPATFQN
LKQLTGLSLQ NNKLSGPVPN LDTVSLRRLN LSNNHLNGSI PSALGGFPSS SFSGNTLLCG
LPLQPCATSS PPPSLTPHIS TPPLPPFPHK EGSKRKLHVS TIIPIAAGGA ALLLLITVII
LCCCIKKKDK REDSIVKVKT LTEKAKQEFG SGVQEPEKNK LVFFNGCSYN FDLEDLLRAS
AEVLGKGSYG TAYKAVLEES TTVVVKRLKE VAAGKREFEQ QMEIISRVGN HPSVVPLRAY
YYSKDEKLMV CDYYPAGNLS SLLHGNRGSE KTPLDWDSRV KITLSAAKGI AHLHAAGGPK
FSHGNIKSSN VIMKQESDAC ISDFGLTPLM AVPIAPMRGA GYRAPEVMET RKHTHKSDVY
SFGVLILEML TGKSPVQSPS RDDMVDLPRW VQSVVREEWT SEVFDIELMR FQNIEEEMVQ
MLQIAMACVA QVPEVRPTMD DVVRMIEEIR VSDSETTRPS SDDNSKPKDS NVQV
